Most rheumatic and musculoskeletal diseases (RMDs) can be placed along a spectrum of
disorders, with autoinflammatory diseases (including monogenic systemic autoinflammatory …

Profound and debilitating fatigue is the most common complaint reported among individuals
with autoimmune disease, such as systemic lupus erythematosus, multiple sclerosis, type 1 …

The neuropsychiatric involvement in systemic lupus erythematosus (NPSLE) is a challenge
for clinicians, both at a diagnostic and therapeutic level. Although in 1999 the American …

Cognitive decline covers a broad spectrum of disorders, not only resulting from brain
diseases but also from systemic diseases, which seriously influence the quality of life and …

Psychoactive drugs frequently contaminate aquatic environments after human consumption,
raising concerns about their residues and ecological harm. This study investigates the …

Several lines of evidence support a role of the immune system in headache pathogenesis,
with particular regard to migraine. Firstly, alterations in cytokine profile and in lymphocyte …

Introduction The pathogenesis of neuropsychiatric systemic lupus erythematosus (NPSLE) is
widely unknown, and the role of autoantibodies is still undetermined. Methods To identify …

Objectives To examine the association between blood-brain barrier (BBB) integrity, brain
volume and cognitive dysfunction in adult patients with systemic lupus erythematosus (SLE) …

Neutrophils are the first cells to be recruited to sites of acute inflammation and contribute to
host defense through phagocytosis, degranulation and neutrophil extracellular traps (NETs) …

Choroid plexus (CP) enlargement is proposed as a marker of neuroinflammation in immune-
mediated conditions. CP involvement has also been hypothesized in the immunopathology …