Surfactant protein D in respiratory and non-respiratory diseases

GL Sorensen - Frontiers in medicine, 2018 - frontiersin.org
Surfactant protein D (SP-D) is a multimeric collectin that is involved in innate immune
defense and expressed in pulmonary, as well as non-pulmonary, epithelia. SP-D exerts …

Chronic obstructive pulmonary disease biomarkers and their interpretation

RA Stockley, DMG Halpin, BR Celli… - American journal of …, 2019 - atsjournals.org
The pathology and impact of chronic obstructive pulmonary disease (COPD) results from an
abnormal inflammatory process resulting in tissue damage with ineffective repair in …

[HTML][HTML] Long-term PM2. 5 exposure in association with chronic respiratory diseases morbidity: a cohort study in northern China

M Yan, H Ge, L Zhang, X Chen, X Yang, F Liu… - Ecotoxicology and …, 2022 - Elsevier
Several literatures have examined the risk of chronic respiratory diseases in association with
short-term ambient PM 2.5 exposure in China. However, little evidence has examined the …

A biomarker model to distinguish types of myocardial infarction and injury

JT Neumann, J Weimann, NA Sörensen… - Journal of the American …, 2021 - jacc.org
Background Discrimination among patients with type 1 myocardial infarction (T1MI), type 2
myocardial infarction (T2MI), and myocardial injury is difficult. Objectives The aim of this …

[HTML][HTML] Ambient particulate matter attenuates Sirtuin1 and augments SREBP1-PIR axis to induce human pulmonary fibroblast inflammation: molecular mechanism of …

CP Tien, CH Chen, WY Lin, CS Liu, KJ Liu… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Evidences have shown a strong link between particulate matter (PM) and increased risk in
human mortality and morbidity, including asthma, chronic obstructive pulmonary disease …

iTRAQ-based proteomics reveals novel biomarkers for idiopathic pulmonary fibrosis

R Niu, Y Liu, Y Zhang, Y Zhang, H Wang, Y Wang… - PloS one, 2017 - journals.plos.org
Idiopathic pulmonary fibrosis (IPF) is a gradual lung disease with a survival of less than 5
years post-diagnosis for most patients. Poor molecular description of IPF has led to …

YKL‐40, CCL18 and SP‐D predict mortality in patients hospitalized with community‐acquired pneumonia

SMC Spoorenberg, SMT Vestjens, GT Rijkers… - …, 2017 - Wiley Online Library
Background and objective The aim of this study was to investigate the prognostic value of
four biomarkers, YKL‐40, chemokine (C‐C motif) ligand 18 (CCL18), surfactant protein‐D …

Using thoracic ultrasound to detect interstitial lung disease in patients with rheumatoid arthritis: a protocol for the diagnostic test accuracy AURORA study

BK Sofíudóttir, SMW Harders, PR Lage-Hansen… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Pulmonary diseases are significant contributors to morbidity and mortality in
patients with rheumatoid arthritis (RA). RA-associated interstitial lung disease (RA-ILD) may …

Association of serum CC16 levels with eosinophilic inflammation and respiratory dysfunction in severe asthma

H Goudarzi, H Kimura, H Kimura, H Makita… - Respiratory …, 2023 - Elsevier
Background There are knowledge gaps in the potential role of Club cell 16-kDa secretory
protein (CC16) in severe asthma phenotypes and type 2 inflammation, as well as the …

The rCC16 protein protects against LPS-induced cell apoptosis and inflammatory responses in human lung pneumocytes

J Lin, J Li, M Shu, W Wu, W Zhang, Q Dou… - Frontiers in …, 2020 - frontiersin.org
Objective Our previous clinical study showed that low lung levels of CC16 strongly influence
the occurrence and development of ARDS. The aim of the present study was to evaluate the …