Self-organization and forces in the mitotic spindle
At the onset of division, the cell forms a spindle, a precise self-constructed micromachine
composed of microtubules and the associated proteins, which divides the chromosomes …
composed of microtubules and the associated proteins, which divides the chromosomes …
Biomechanics of chromosome alignment at the spindle midplane
During metaphase, chromosomes are aligned in a lineup at the equatorial plane of the
spindle to ensure synchronous poleward movement of chromatids in anaphase and proper …
spindle to ensure synchronous poleward movement of chromatids in anaphase and proper …
Super-resolved live-cell imaging using random illumination microscopy
Current super-resolution microscopy (SRM) methods suffer from an intrinsic complexity that
might curtail their routine use in cell biology. We describe here random illumination …
might curtail their routine use in cell biology. We describe here random illumination …
Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling
C Edelmaier, AR Lamson, ZR Gergely, S Ansari… - Elife, 2020 - elifesciences.org
The essential functions required for mitotic spindle assembly and chromosome biorientation
and segregation are not fully understood, despite extensive study. To illuminate the …
and segregation are not fully understood, despite extensive study. To illuminate the …
Length-dependent poleward flux of sister kinetochore fibers promotes chromosome alignment
Chromosome alignment at the spindle equator promotes proper chromosome segregation
and depends on pulling forces exerted at kinetochore fiber tips together with polar ejection …
and depends on pulling forces exerted at kinetochore fiber tips together with polar ejection …
Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission
M Zeeshan, DJP Ferguson, S Abel… - Life science …, 2019 - life-science-alliance.org
Eukaryotic flagella are conserved microtubule-based organelles that drive cell motility.
Plasmodium, the causative agent of malaria, has a single flagellate stage: the male gamete …
Plasmodium, the causative agent of malaria, has a single flagellate stage: the male gamete …
Plasmodium kinesin-8X associates with mitotic spindles and is essential for oocyst development during parasite proliferation and transmission
Kinesin-8 proteins are microtubule motors that are often involved in regulation of mitotic
spindle length and chromosome alignment. They move towards the plus ends of spindle …
spindle length and chromosome alignment. They move towards the plus ends of spindle …
Transcriptomic profiling of taproot growth and sucrose accumulation in sugar beet (Beta vulgaris L.) at different developmental stages
YF Zhang, GL Li, XF Wang, YQ Sun, SY Zhang - PloS one, 2017 - journals.plos.org
In sugar beet (Beta vulgaris L.), taproot weight and sucrose content are the important
determinants of yield and quality. However, high yield and low sucrose content are two …
determinants of yield and quality. However, high yield and low sucrose content are two …
Metaphase kinetochore movements are regulated by kinesin-8 motors and microtubule dynamic instability
During metaphase, sister chromatids are connected to microtubules extending from the
opposite spindle poles via kinetochores to protein complexes on the chromosome …
opposite spindle poles via kinetochores to protein complexes on the chromosome …
Kinesin-8 motors: regulation of microtubule dynamics and chromosome movements
Y Lin, YL Wei, ZY She - Chromosoma, 2020 - Springer
Microtubules are essential for intracellular transport, cell motility, spindle assembly, and
chromosome segregation during cell division. Microtubule dynamics regulate the proper …
chromosome segregation during cell division. Microtubule dynamics regulate the proper …