Complex genetic and physiological variations as well as environmental factors that drive
emergence of chromosomal instability, development of unscheduled cell death, skewed …

Cisplatin, carboplatin and oxaliplatin are platinum-based drugs that are widely used in
cancer chemotherapy. Platinum–DNA adducts, which are formed following uptake of the …

V (D) J recombination assembles immunoglobulin and T cell receptor genes during
lymphocyte development through a series of carefully orchestrated DNA breakage and …

HMGB proteins are members of the High Mobility Group (HMG) superfamily, possessing a
unique DNA-binding domain, the HMG-box, which can bind non-B-type DNA structures …

The HMG-box proteins, one of the three classes of high mobility group (HMG) chromosomal
proteins 1 1The recent revisions of the nomenclature for the HMG proteins are detailed on p …

V (D) J recombination proceeds through a series of protein: DNA complexes mediated in
part by the RAG1 and RAG2 proteins. These proteins are responsible for sequence-specific …

High mobility group (HMG) proteins are chromatin proteins endowed with 'architectural'
capabilities. HMGA proteins are moderately sequence-specific, and help build …

High mobility group box protein 1 (HMGB1) is a highly versatile, abundant, and ubiquitously
expressed, non-histone chromosomal protein, which belongs to the HMGB family of …

High-Mobility Group (HMG) chromosomal proteins are the most numerous nuclear non-
histone proteins. HMGB domain proteins are the most abundant and well-studied HMG …

Abstract V (D) J recombination in the vertebrate immune system generates a highly diverse
population of immunoglobulins and T-cell receptors by combinatorial joining of segments of …