[HTML][HTML] The many faces of C/EBPδ and their relevance for inflammation and cancer

K Balamurugan, E Sterneck - International journal of biological …, 2013 - ncbi.nlm.nih.gov
The CCAAT/enhancer binding protein delta (CEBPD, C/EBPδ) is a transcription factor that
modulates many biological processes including cell differentiation, motility, growth arrest …

Biological roles of CCAAT/Enhancer-binding protein delta during inflammation

CY Ko, WC Chang, JM Wang - Journal of biomedical science, 2015 - Springer
CCAAT/enhancer-binding protein delta (CEBPD) belongs to the CCAAT/enhancer-binding
protein family, and these proteins function as transcription factors in many biological …

C/EBPβ and C/EBPδ transcription factors: Basic biology and roles in the CNS

M Pulido-Salgado, JM Vidal-Taboada, J Saura - Progress in Neurobiology, 2015 - Elsevier
CCAAT/enhancer binding protein (C/EBP) β and C/EBPδ are transcription factors of the
basic-leucine zipper class which share phylogenetic, structural and functional features. In …

PERK signaling through C/EBPδ contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells

N Sheshadri, DK Poria, S Sharan, Y Hu, C Yan… - Cell death & …, 2021 - nature.com
Cancer cells experience endoplasmic reticulum (ER) stress due to activated oncogenes and
conditions of nutrient deprivation and hypoxia. The ensuing unfolded protein response …

C/EBPδ links IL-6 and HIF-1 signaling to promote breast cancer stem cell-associated phenotypes

K Balamurugan, D Mendoza-Villanueva, S Sharan… - Oncogene, 2019 - nature.com
To improve cancer patient outcome significantly, we must understand the mechanisms
regulating stem-like cancer cells, which have been implicated as a cause of metastasis and …

High-throughput formation and image-based analysis of basal-in mammary organoids in 384-well plates

S Lee, J Chang, SM Kang, E Parigoris, JH Lee… - Scientific Reports, 2022 - nature.com
This manuscript describes a new method for forming basal-in MCF10A organoids using
commercial 384-well ultra-low attachment (ULA) microplates and the development of …

Nilotinib and bosutinib modulate pre-plaque alterations of blood immune markers and neuro-inflammation in Alzheimer's disease models

I Lonskaya, ML Hebron, ST Selby, RS Turner… - Neuroscience, 2015 - Elsevier
Alzheimer's disease (AD) brains exhibit plaques and tangles in association with
inflammation. The non-receptor tyrosine kinase Abl is linked to neuro-inflammation in AD …

FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4

K Balamurugan, S Sharan, KD Klarmann… - Nature …, 2013 - nature.com
Abstract Toll-like receptor 4 (Tlr4) has a pivotal role in innate immune responses, and the
transcription factor CCAAT/enhancer binding protein delta (C/EBPδ, Cebpd) is a Tlr4 …

[HTML][HTML] Aberrant regulation of FBW7 in cancer

L Wang, X Ye, Y Liu, W Wei, Z Wang - Oncotarget, 2014 - ncbi.nlm.nih.gov
Abstract FBW7 (F-box and WD repeat domain-containing 7) or Fbxw7 is a tumor suppressor,
which promotes the ubiquitination and subsequent degradation of numerous oncoproteins …

[HTML][HTML] CCAAT/enhancer-binding proteins in fibrosis: Complex roles beyond conventional understanding

L Wang, J Feng, Y Deng, Q Yang, Q Wei, D Ye, X Rong… - Research, 2022 - spj.science.org
CCAAT/enhancer-binding proteins (C/EBPs) are a family of at least six identified
transcription factors that contain a highly conserved basic leucine zipper domain and …