The tremendous biomedical potential of bacterial extracellular vesicles

J Xie, Q Li, F Haesebrouck, L Van Hoecke… - Trends in …, 2022 - cell.com
Bacterial extracellular vesicles (bEVs) are nano-sized, lipid membrane-delimited particles
filled with bacteria-derived components. They have important roles in the physiology and …

Bacterial extracellular vesicles and their interplay with the immune system

E Doré, E Boilard - Pharmacology & Therapeutics, 2023 - Elsevier
The mammalian intestinal tract harbors trillions of microorganisms confined within this space
by mucosal barriers. Despite these barriers, bacterial components may still be found …

Experimental studies using OMV in a new platform of SARS-CoV-2 vaccines

EB Gaspar, CR Prudencio… - Human Vaccines & …, 2021 - Taylor & Francis
Although COVID-19 vaccines have recently been approved for emergency use, search for
new vaccines are still urgent, since the access of the countries, especially the poorest, to the …

[HTML][HTML] Avidity assay to test functionality of anti-SARS-Cov-2 antibodies

EB Gaspar, E De Gaspari - Vaccine, 2021 - ncbi.nlm.nih.gov
The ongoing status of the Coronavirus pandemic in Brazil, as notoriously reported
(https://covid. saude. gov. br/), highlights the public health efforts still necessary to comply …

A novel cold-chain free VCG-based subunit vaccine protects against Chlamydia abortus-induced neonatal mortality in a pregnant mouse model

S Richardson, CR Bell, F Medhavi, T Tanner… - Frontiers in …, 2023 - frontiersin.org
Chlamydia abortus (Cab) causes spontaneous abortion and neonatal mortality in infected
ruminants and pregnant women. Most Cab infections are asymptomatic, although they can …

Non-infectious outer membrane vesicles derived from Brucella abortus S19Δper as an alternative acellular vaccine protects mice against virulent challenge

KS Solanki, R Varshney, S Qureshi, P Thomas… - International …, 2021 - Elsevier
The prime human and animal safety issues accentuate the search of promising newer
alternative vaccine candidates to resolve complications associated with the live attenuated …

Gut Microbe-Derived Outer Membrane Vesicles: A Potential Platform to Control Cecal Load of Campylobacter jejuni

A Singh, A Khan, T Ghosh, S Mondal… - ACS Infectious …, 2021 - ACS Publications
Acute diarrheal illness and gastroenteritis caused by Campylobacter jejuni infection remain
significant public health risks in developing countries with substantial mortality and morbidity …

Immunological Effects of Dimethyldioctadecylammonium Bromide and Saponin as Adjuvants for Outer Membrane Vesicles from Neisseria meningitidis

VA Correa, AI Portilho, E De Gaspari - Diseases, 2022 - mdpi.com
The meningococcal disease is a global health threat, but is preventable through vaccination.
Adjuvants improve meningococcal vaccines and are able to trigger different aspects of the …

Recombinant ClearColi™-derived outer membrane vesicles as an effective carrier for development of neoepitope-based vaccine candidate against colon carcinoma

E Sharif, N Nezafat, E Mohit - International Immunopharmacology, 2024 - Elsevier
Background Colorectal carcinoma (CRC) is the third most common cancer worldwide, with
high clonal heterogeneity due to somatic mutations. Poly neoepitope vaccines can inhibit …

Outer membrane vesicles as a platform for the discovery of antibodies to bacterial pathogens

EK Lei, A Azmat, KA Henry, G Hussack - Applied Microbiology and …, 2024 - Springer
Bacterial outer membrane vesicles (OMVs) are nanosized spheroidal particles shed by gram-
negative bacteria that contain biomolecules derived from the periplasmic space, the …