Oligodendrocyte death and myelin loss in the cuprizone model: an updated overview of the intrinsic and extrinsic causes of cuprizone demyelination
Background The dietary consumption of cuprizone–a copper chelator–has long been known
to induce demyelination of specific brain structures and is widely used as model of multiple …
to induce demyelination of specific brain structures and is widely used as model of multiple …
The regulation of the ZBP1‐NLRP3 inflammasome and its implications in pyroptosis, apoptosis, and necroptosis (PANoptosis)
M Zheng, TD Kanneganti - Immunological reviews, 2020 - Wiley Online Library
ZBP1 has been characterized as a critical innate immune sensor of not only viral RNA
products but also endogenous nucleic acid ligands. ZBP1 sensing of the Z‐RNA produced …
products but also endogenous nucleic acid ligands. ZBP1 sensing of the Z‐RNA produced …
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L Galluzzi, I Vitale, SA Aaronson, JM Abrams… - Cell Death & …, 2018 - nature.com
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …
guidelines for the definition and interpretation of cell death from morphological, biochemical …
The double-edged functions of necroptosis
K Ye, Z Chen, Y Xu - Cell Death & Disease, 2023 - nature.com
Necroptosis refers to a regulated form of cell death induced by a variety of stimuli. Although it
has been implicated in the pathogenesis of many diseases, there is evidence to support that …
has been implicated in the pathogenesis of many diseases, there is evidence to support that …
DNA damage and the balance between survival and death in cancer biology
WP Roos, AD Thomas, B Kaina - Nature Reviews Cancer, 2016 - nature.com
DNA is vulnerable to damage resulting from endogenous metabolites, environmental and
dietary carcinogens, some anti-inflammatory drugs, and genotoxic cancer therapeutics …
dietary carcinogens, some anti-inflammatory drugs, and genotoxic cancer therapeutics …
TNF and ROS crosstalk in inflammation
Tumor necrosis factor (TNF) is tremendously important for mammalian immunity and cellular
homeostasis. The role of TNF as a master regulator in balancing cell survival, apoptosis and …
homeostasis. The role of TNF as a master regulator in balancing cell survival, apoptosis and …
Necroptosis: mechanisms and relevance to disease
Necroptosis is a form of regulated cell death that critically depends on receptor-interacting
serine-threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like (MLKL) and …
serine-threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like (MLKL) and …
Regulated necrosis: the expanding network of non-apoptotic cell death pathways
TV Berghe, A Linkermann, S Jouan-Lanhouet… - … reviews Molecular cell …, 2014 - nature.com
Cell death research was revitalized by the understanding that necrosis can occur in a highly
regulated and genetically controlled manner. Although RIPK1 (receptor-interacting protein …
regulated and genetically controlled manner. Although RIPK1 (receptor-interacting protein …
Regulation of NF-κB by TNF family cytokines
The NF-κB family of inducible transcription factors is activated in response to a variety of
stimuli. Amongst the best-characterized inducers of NF-κB are members of the TNF family of …
stimuli. Amongst the best-characterized inducers of NF-κB are members of the TNF family of …
Regulation of tumour necrosis factor signalling: live or let die
Tumour necrosis factor (TNF) is a pro-inflammatory cytokine that has important roles in
mammalian immunity and cellular homeostasis. Deregulation of TNF receptor (TNFR) …
mammalian immunity and cellular homeostasis. Deregulation of TNF receptor (TNFR) …