During the last two decades, DNA-based molecular markers have been extensively utilized
for a variety of studies in both plant and animal systems. One of the major uses of these …

There is a growing appreciation that chromosome inversions affect rates of adaptation,
speciation, and the evolution of sex chromosomes. Comparative genomic studies have …

A refined physical map of chromosome 17q21. 31 uncovered a 900-kb inversion
polymorphism. Chromosomes with the inverted segment in different orientations represent …

In eukaryotes, unlike in bacteria, gene order has typically been assumed to be random.
However, the first statistically rigorous analyses of complete genomes, together with the …

Understanding the genetic underpinnings of adaptive change is a fundamental but largely
unresolved problem in evolutionary biology. D rosophila melanogaster, an ancestrally …

Inversions are structural mutations that reverse the sequence of a chromosome segment
and reduce the effective rate of recombination in the heterozygous state. They play a major …

We have sequenced the genome of a second Drosophila species, Drosophila
pseudoobscura, and compared this to the genome sequence of Drosophila melanogaster, a …

Clines in chromosomal inversion polymorphisms—presumably driven by climatic gradients—
are common but there is surprisingly little evidence for selection acting on them. Here we …

The molting process in arthropods is regulated by steroid hormones acting via nuclear
receptor proteins. The most common molting hormone is the ecdysteroid, 20 …

Both classical and recent studies suggest that chromosomal inversion polymorphisms are
important in adaptation and speciation. However, biases in discovery and reporting of …