Drugs that induce or cause deterioration of myasthenia gravis: an update

S Sheikh, U Alvi, B Soliven, K Rezania - Journal of Clinical Medicine, 2021 - mdpi.com
Myasthenia gravis (MG) is an autoimmune neuromuscular disorder which is characterized
by presence of antibodies against acetylcholine receptors (AChRs) or other proteins of the …

Statins neuromuscular adverse effects

S Attardo, O Musumeci, D Velardo… - International journal of …, 2022 - mdpi.com
Statins are drugs widely prescribed in high-risk patients for cerebrovascular or
cardiovascular diseases and are, usually, safe and well tolerated. However, these drugs …

Autoimmune myasthenia gravis: emerging clinical and biological heterogeneity

MN Meriggioli, DB Sanders - The Lancet Neurology, 2009 - thelancet.com
Acquired myasthenia gravis (MG) is an autoimmune disorder of the neuromuscular junction
in which patients experience fluctuating skeletal muscle weakness that often affects selected …

Clinical significance of serum albumin and implications of FcRn inhibitor treatment in IgG-mediated autoimmune disorders

ES Ward, D Gelinas, E Dreesen… - Frontiers in …, 2022 - frontiersin.org
Serum albumin (SA), the most abundant soluble protein in the body, maintains plasma
oncotic pressure and regulates the distribution of vascular fluid and has a range of other …

Incidence, mortality, and economic burden of myasthenia gravis in China: a nationwide population-based study

J Chen, DC Tian, C Zhang, Z Li, Y Zhai… - The Lancet Regional …, 2020 - thelancet.com
Background Myasthenia gravis (MG) is the most common primary disorder of neuromuscular
transmission, but the incidence of MG in China is unknown. We conducted the first …

Adverse effects of statins-mechanisms and consequences

J Beltowski, G Wojcicka… - Current drug …, 2009 - ingentaconnect.com
Statins inhibit 3-hydroxy-3-methylglutarylcoenzyme A (HMG-CoA) reductase, the rate-
limiting enzyme in cholesterol biosynthesis, which converts HMG-CoA to mevalonate …

Myasthenia gravis and risks for comorbidity

NE Gilhus, A Nacu, JB Andersen… - European journal of …, 2015 - Wiley Online Library
Myasthenia gravis (MG) is an autoimmune disorder leading to skeletal muscle weakness
and fatigability. MG subgroups are defined according to pathogenetic autoantibody (against …

Risk factors and drug interactions predisposing to statin-induced myopathy: implications for risk assessment, prevention and treatment

YS Chatzizisis, KC Koskinas, G Misirli, C Vaklavas… - Drug safety, 2010 - Springer
HMG-CoA reductase inhibitors ('statins') represent the most effective and widely prescribed
drugs currently available for the reduction of low-density lipoprotein cholesterol, a critical …

Toxic and drug-induced myopathies

MC Dalakas - Journal of Neurology, Neurosurgery & Psychiatry, 2009 - jnnp.bmj.com
Drugs used for therapeutic interventions either alone or in combination may sometimes
cause unexpected toxicity to the muscles, resulting in a varying degree of symptomatology …

Statins and myotoxic effects associated with anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase autoantibodies: an observational study in Japan

Y Watanabe, S Suzuki, H Nishimura, K Murata… - Medicine, 2015 - journals.lww.com
Statins have a variety of myotoxic effects and can trigger the development of inflammatory
myopathies or myasthenia gravis (MG) mediated by immunomodulatory properties …