An estimated 58 million people have survived tuberculosis since 2000, yet many of them will
suffer from post-tuberculosis lung disease (PTLD). PTLD results from a complex interplay …

Adolescence is characterised by a substantial increase in the incidence of tuberculosis, a
known fact since the early 20th century. Most of the world's adolescents live in low-income …

Background To end the global tuberculosis epidemic, latent tuberculosis infection needs to
be addressed. All standard treatments for latent tuberculosis contain drugs to which …

We currently have a binomial approach to managing tuberculosis. Those with active
disease, ideally confirmed microbiologically, are treated with a standard 6-month, multi-drug …

Tuberculosis (TB) in humans is caused by Mycobacterium tuberculosis (Mtb). It is estimated
that 70 million children (< 15 years) are currently infected with Mtb, with 1.2 million each year …

Tuberculosis (TB), the world's deadliest bacterial infection, afflicts more human males than
females, with a male/female (M/F) ratio of 1.7. Sex disparities in TB prevalence …

Human immunodeficiency virus (HIV) and Mycobacterium tuberculosis (Mtb) are pathogens
responsible for millions of new infections each year; together, they cause high morbidity and …

Objectives New tests are needed to overcome the limitations of existing immunodiagnostic
tests for tuberculosis (TB) infection, including their inability to differentiate between active TB …

Research on the pathogenesis of tuberculosis (TB) has been hamstrung for half a century by
the paradigm that granulomas are the hallmark of active disease. Human TB, in fact …

Managing pediatric tuberculosis (TB) remains a public health problem requiring urgent and
long-lasting solutions as TB is one of the top ten causes of ill health and death in children as …