[HTML][HTML] Epigenetics and congenital heart diseases
L Linglart, D Bonnet - Journal of Cardiovascular Development and …, 2022 - mdpi.com
Congenital heart disease (CHD) is a frequent occurrence, with a prevalence rate of almost
1% in the general population. However, the pathophysiology of the anomalous heart …
1% in the general population. However, the pathophysiology of the anomalous heart …
[HTML][HTML] Cardiac Development and Factors Influencing the Development of Congenital Heart Defects (CHDs): Part I
M Zubrzycki, R Schramm, A Costard-Jäckle… - International Journal of …, 2024 - mdpi.com
The traditional description of cardiac development involves progression from a cardiac
crescent to a linear heart tube, which in the phase of transformation into a mature heart …
crescent to a linear heart tube, which in the phase of transformation into a mature heart …
Downregulation of NUP93 aggravates hypoxia-induced death of cardiomyocytes in vitro through abnormal regulation of gene transcription
L Pan, X Song, J Song, C Shi, Z Wang… - Acta Pharmacologica …, 2023 - nature.com
Nuclear pore complex in the nuclear envelope plays an important role in controlling the
transportation of RNAs, proteins and other macromolecules between the nucleus and …
transportation of RNAs, proteins and other macromolecules between the nucleus and …
Discovery of 1, 2, 4-Triazole-3-thione Derivatives as Potent and Selective DCN1 Inhibitors for Pathological Cardiac Fibrosis and Remodeling
ZX He, G Gao, H Qiao, G Dong, Z Dan… - Journal of Medicinal …, 2024 - ACS Publications
DCN1, a critical co-E3 ligase during the neddylation process, is overactivated in many
diseases, such as cancers, heart failure as well as fibrotic diseases, and has been regarded …
diseases, such as cancers, heart failure as well as fibrotic diseases, and has been regarded …
[HTML][HTML] Polycomb repressive complex 2 controls cardiac cell fate decision via interacting with RNA: Promiscuously or well-ordered
G Wang, H Ye, X Wang, B Liu - Frontiers in Genetics, 2022 - frontiersin.org
The epigenetic landscape determines cell fate during heart development. Polycomb
repressive complex 2 (PRC2) mediates histone methyltransferase activity during cardiac cell …
repressive complex 2 (PRC2) mediates histone methyltransferase activity during cardiac cell …
Transient stabilization of human cardiovascular progenitor cells from human pluripotent stem cells in vitro reflects stage-specific heart development in vivo
E Bolesani, D Bornhorst, LM Iyer… - Cardiovascular …, 2024 - academic.oup.com
Aims Understanding the molecular identity of human pluripotent stem cell (hPSC)-derived
cardiac progenitors and mechanisms controlling their proliferation and differentiation is …
cardiac progenitors and mechanisms controlling their proliferation and differentiation is …
Transient stabilization of human cardiovascular progenitor cells from human pluripotent stem cells in vitro reflects stage-specific heart development in vivo
E Bolesani, D Bornhorst, LM Iyer… - Cardiovascular …, 2024 - academic.oup.com
Aims Understanding the molecular identity of human pluripotent stem cell (hPSC)-derived
cardiac progenitors and mechanisms controlling their proliferation and differentiation is …
cardiac progenitors and mechanisms controlling their proliferation and differentiation is …
Three‐dimensional genome structure and function
H Liu, H Tsai, M Yang, G Li, Q Bian, G Ding, D Wu… - MedComm, 2023 - Wiley Online Library
Linear DNA undergoes a series of compression and folding events, forming various three‐
dimensional (3D) structural units in mammalian cells, including chromosomal territory …
dimensional (3D) structural units in mammalian cells, including chromosomal territory …
[HTML][HTML] The benign nature and rare occurrence of cardiac myxoma as a possible consequence of the limited cardiac proliferative/regenerative potential: a systematic …
O Shafi, G Siddiqui, HA Jaffry - BMC cancer, 2023 - Springer
Abstract Background Cardiac Myxoma is a primary tumor of heart. Its origins, rarity of the
occurrence of primary cardiac tumors and how it may be related to limited cardiac …
occurrence of primary cardiac tumors and how it may be related to limited cardiac …
Dysregulations in Cardiogenic Mechanisms by TGF-beta and Angiotensin II in Cardiac Remodeling Post-Ischemic Injury: a systematic review
O Shafi, K Zahra, HH Shah - medRxiv, 2024 - medrxiv.org
Objective The objective of this study is to look into how TGF-beta and Angiotensin II disrupt
cardiogenic regulators (Isl1, Brg1/Baf60-Smarcd3 complex, Nkx2-5, GATA4, Tbx5, Mef2c …
cardiogenic regulators (Isl1, Brg1/Baf60-Smarcd3 complex, Nkx2-5, GATA4, Tbx5, Mef2c …