MicroRNA: function, detection, and bioanalysis

H Dong, J Lei, L Ding, Y Wen, H Ju, X Zhang - Chemical reviews, 2013 - ACS Publications
Mature microRNAs (miRNAs) are a class of evolutionally conserved, single-stranded, small
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …

Recent advances on nanomaterials-based fluorimetric approaches for microRNAs detection

M Norouzi, S Yasamineh, M Montazeri… - Materials Science and …, 2019 - Elsevier
MicroRNAs are types of small single-stranded endogenous highly conserved non-coding
RNAs, which play main regulatory functions in a wide range of cellular and physiological …

Metal-organic framework nanoreactor-based electrochemical biosensor coupled with three-dimensional DNA walker for label-free detection of microRNA

L Kong, S Lv, Z Qiao, Y Yan, J Zhang, S Bi - Biosensors and Bioelectronics, 2022 - Elsevier
MicroRNAs (miRNAs), serving as the regulators for gene expression and cellular function,
have emerged as the important biomarkers for diagnosis of cancers. In this study, a label …

A highly sensitive and selective electrochemical biosensor for direct detection of microRNAs in serum

Y Ren, H Deng, W Shen, Z Gao - Analytical chemistry, 2013 - ACS Publications
On the basis of hybridized target microRNA (miRNA) strand initiated cleavage of hybridized
deoxyribonucleic acid (DNA) capture probes (CPs) by a duplex-specific nuclease (DSN), a …

Enhanced DNA entropy-driven circuit by locked nucleic acids and simulation-guided localization

Q Kou, J Yang, L Wang, H Zhao… - ACS Applied Materials …, 2023 - ACS Publications
Signal amplification methods based on DNA molecular interactions are promising tools for
detecting various biomarkers in low abundance. The entropy-driven circuit (EDC), as an …

Carbon nanotube-based label-free electrochemical biosensor for sensitive detection of miRNA-24

F Li, J Peng, J Wang, H Tang, L Tan, Q Xie… - Biosensors and …, 2014 - Elsevier
The recent findings concerning the function of microRNAs (miRNAs) and the relationship
between miRNA levels with specific disease highlight the need for miRNA detection. In this …

Ultrasensitive detection of cancer biomarker microRNA by amplification of fluorescence of lanthanide nanoprobes

L Lu, D Tu, Y Liu, S Zhou, W Zheng, X Chen - Nano Research, 2018 - Springer
Sensitive detection of cancer biomarker microRNAs (miRNAs) is of vital importance for
cancer diagnosis and treatment. Nonetheless, the detection sensitivity in the existing miRNA …

Advanced methods for microRNA biosensing: a problem-solving perspective

R D'Agata, G Spoto - Analytical and bioanalytical chemistry, 2019 - Springer
MicroRNAs (miRNAs) present several features that make them more difficult to analyze than
DNA and RNA. For this reason, efforts have been made in recent years to develop …

“Getting the best sensitivity from on-capillary fluorescence detection in capillary electrophoresis”–A tutorial

VA Galievsky, AS Stasheuski, SN Krylov - Analytica Chimica Acta, 2016 - Elsevier
Abstract Capillary electrophoresis with Laser-Induced Fluorescence (CE-LIF) detection is
being applied to new analytical problems which challenge both the power of CE separation …

Trace microRNA quantification by means of plasmon-enhanced hybridization chain reaction

F Yin, H Liu, Q Li, X Gao, Y Yin, D Liu - Analytical chemistry, 2016 - ACS Publications
Quantifying trace microRNAs (miRNAs) is extremely important in a number of biomedical
applications but remains a great challenge. Here we present an enzyme-free amplification …