Transitions between epithelial and mesenchymal phenotypes–the epithelial to
mesenchymal transition (EMT) and its reverse the mesenchymal to epithelial transition …

Most of the cancers are still incurable human diseases. According to recent findings,
especially targeting cancer stem cells (CSCs) is the most promising therapeutic strategy …

While there are myriad mechanisms of primary and acquired resistance to conventional and
next-generation hormonal therapies in prostate cancer, the potential role of androgen …

Docetaxel is the main treatment for advanced castration‐resistant prostate cancer; however,
resistance eventually occurs. The development of intratumoral drug‐resistant …

Alteration to the expression and activity of androgen receptor (AR) coregulators in prostate
cancer is an important mechanism driving disease progression and therapy resistance …

Abstract MicroRNA-375 (miR-375) is frequently elevated in prostate tumors and cell-free
fractions of patient blood, but its role in genesis and progression of prostate cancer is poorly …

Epithelial-to-mesenchymal plasticity (EMP) has been linked to metastasis, stemness, and
drug resistance. In prostate cancer, EMP has been associated with both suppression and …

Three-dimensional (3D) cell cultures allow the mimic of functions of living tissues and
provide key information encoded in tissue architecture. Considered the pivotal role of …

Ionizing radiation (IR) has been shown to play a crucial role in the treatment of glioblastoma
(GBM; grade IV) and non-small-cell lung cancer (NSCLC). Nevertheless, recent studies …

Cancers of the reproductive organs have a strong association with mitochondrial defects,
and a deeper understanding of the role of this organelle in preneoplastic–neoplastic …