Non-alcoholic fatty liver disease (NAFLD) has become the leading cause of chronic liver
diseases worldwide, causing considerable liver-related mortality and morbidity. During the …

Abstract Purpose of the Review Mitochondrial dysfunction has long been proposed to play a
crucial role in the pathogenesis of a considerable number of disorders, such as …

BACKGROUND & AIMS: Glucagon-like peptide-1 (GLP-1), a gut-derived peptide degraded
by dipeptidyl peptidase-4 (DPP4), stimulates insulin secretion in response to nutrients, yet its …

Insulin resistance (IR) and mitochondrial dysfunction play a central role in the
pathophysiology of nonalcoholic fatty liver disease (NAFLD). We hypothesized that genetic …

Non‐alcoholic fatty liver disease (NAFLD) is recognized as the most common type of chronic
liver disease in Western countries and the leading cause of cryptogenic cirrhosis. Insulin …

A growing body of evidence supports the notion that epigenetic changes such as DNA
methylation and histone modifications, both involving chromatin remodeling, contribute to …

The underlying mechanism and pathogenesis of NAFLD remain elusive despite ongoing
researches to make significant advances in the understanding of its natural history …

Non-alcoholic fatty liver disease (NAFLD) encompasses pure steatosis through nonalcoholic
steatohepatitis (NASH) and is the most common cause of chronic liver disease in Western …

OBJECTIVES: We evaluated circulating levels of biomarkers of atherosclerosis (soluble
intercellular adhesion molecule: sICAM-1, plasminogen activator inhibitor: PAI-1 and soluble …

Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming a world‐wide public health
problem. NAFLD represents a spectrum of disease ranging from “simple steatosis”, which is …