The concept of transient nanometric domains known as lipid rafts has brought interest to
reassess the validity of the Singer–Nicolson model of a fluid bilayer for cell membranes …

Abstract The Mitogen-Activated Protein Kinase (MAPK) signaling pathways constitute one of
the most important and evolutionarily conserved mechanisms for the perception of …

Biological membranes are partitioned into functional zones termed membrane
microdomains, which contain specific lipids and proteins,–. The composition and …

To grow, eukaryotic cells must expand by inserting glycerolipids, sphingolipids, sterols, and
proteins into their plasma membrane, and maintain the proper levels and bilayer distribution …

The survival of eukaryotic organisms during environmental changes is largely dependent on
the adaptive responses elicited by signal transduction cascades, including those regulated …

Cellular blebbing, caused by local alterations in cell-surface tension, has been shown to
increase the invasiveness of cancer cells. However, the regulatory mechanisms balancing …

One of the best characterized fungal membrane microdomains is the MCC/eisosome. The
MCC (membrane compartment of Can1) is an evolutionarily conserved ergosterol-rich …

Eisosomes are large hemitubular structures that underlie the invaginated microdomains in
the plasma membrane of various ascomycetous fungi, lichens and unicellular algae. In …

In eukaryotic cells, the highly conserved Target of Rapamycin (TOR) and the Mitogen
Activated Protein Kinase (MAPK) signaling pathways elicit adaptive responses to extra-and …

Produced by a newly isolated Streptomycetes strain, meijiemycin is a gigantic linear polyene-
polyol that exhibits structural features not seen in other members of the polyene-polyol …