Mucosal and cutaneous human papillomavirus infections and cancer biology

T Gheit - Frontiers in Oncology, 2019 - frontiersin.org
Papillomaviridae is a family of small non-enveloped icosahedral viruses with double-
stranded circular DNA. More than 200 different human papillomaviruses (HPVs) have been …

[HTML][HTML] Mechanisms and strategies of papillomavirus replication

AA McBride - Biological chemistry, 2017 - degruyter.com
Animal and human papillomaviruses (HPVs) replicate persistently in specific types of
stratified epithelia of their host. After the initial infection, the viral genome replicates at low …

The EccDNA Replicon: A Heritable, Extranuclear Vehicle That Enables Gene Amplification and Glyphosate Resistance in Amaranthus palmeri

WT Molin, A Yaguchi, M Blenner, CA Saski - The Plant Cell, 2020 - academic.oup.com
Gene copy number variation is a predominant mechanism used by organisms to respond to
selective pressures from the environment. This often results in unbalanced structural …

Molecular and cellular functions of the Warsaw breakage syndrome DNA helicase DDX11

FM Pisani, E Napolitano, LMR Napolitano, S Onesti - Genes, 2018 - mdpi.com
DDX11/ChlR1 (Chl1 in yeast) is a DNA helicase involved in sister chromatid cohesion and
in DNA repair pathways. The protein belongs to the family of the iron–sulphur cluster …

Hitchhiking of viral genomes on cellular chromosomes

TL Coursey, AA McBride - Annual review of virology, 2019 - annualreviews.org
Persistent viral infections require a host cell reservoir that maintains functional copies of the
viral genome. To this end, several DNA viruses maintain their genomes as …

Uncovering the role of the E1 protein in different stages of human papillomavirus 18 genome replication

A Piirsoo, M Kala, E Sankovski, M Ustav… - Journal of …, 2020 - Am Soc Microbiol
The life cycle of human papillomaviruses (HPVs) comprises three distinct phases of DNA
replication: initial amplification, maintenance of the genome copy number at a constant level …

The genome stability maintenance DNA helicase DDX11 and its role in cancer

M Mahtab, A Boavida, D Santos, FM Pisani - Genes, 2021 - mdpi.com
DDX11/ChlR1 is a super-family two iron–sulfur cluster containing DNA helicase with roles in
DNA replication and sister chromatid cohesion establishment, and general chromosome …

Plasmid partitioning by human tumor viruses

YF Chiu, B Sugden - Journal of virology, 2018 - Am Soc Microbiol
The human tumor viruses that replicate as plasmids (we use the term plasmid to avoid any
confusion in the term episome, which was coined to mean DNA elements that occur both …

Phosphorylation of a conserved tyrosine in the papillomavirus E2 protein regulates Brd4 binding and viral replication

M DeSmet, L Jose, N Isaq, EJ Androphy - Journal of Virology, 2019 - Am Soc Microbiol
The papillomavirus (PV) E2 protein coordinates viral transcription and genome replication.
Following a strategy to identify amino acids in E2 that are posttranslationally modified, we …

Differential requirement of the transcription factor HOXC13 for the stable maintenance of human papillomavirus genome among high-risk genotypes

Y Ishii, S Mori, T Takeuchi, I Kukimoto - Virology, 2024 - Elsevier
The viral genome of the high-risk human papillomavirus (HPV), the causative agent of
cervical cancer, is stably maintained as extrachromosomal episomes that establish …