Biocatalysis has emerged as a strong tool for the synthesis of active pharmaceutical
ingredients (APIs). In the early twentieth century, whole cell biocatalysis was used to …

A series of trans-5-substituted-acenaphthene-1, 2-diols were obtained in 21–72% yield with
97–100% ee by baker's yeast-mediated reduction of the corresponding acenaphthylene-1, 2 …

This work describes the chemoselective bioreduction of (1E, 4E)-1, 5-bis (4-methoxyphenyl)-
1, 4-pentadien-3-one (1) mediated by baker's yeast (BY, Saccharomyces cerevisiae cells) in …

Fourteen chiral α-and β-keto alcohols 2a–2r were synthesized by the asymmetric reduction
of their corresponding diketones 1a–1r via baker's yeast. In addition, ten corresponding …

Tetradentate Schiff base ligands. L1=(2Z)-2, 2 ((4-methyl-1, 2-phenylene) bis
(azoneylidine))) bis (acenaphthylene-1 (2H)-one, L2=(2Z, 2E)-2, 2'-((4-nitro-1, 2-phenylene) …

Regio-and enantioselective reduction of substituted acenaphthenequinones were
conducted under mild reaction conditions using plant enzymatic systems. A screening of 15 …

A Schiff base,(E)-ethyl-4-(2-oxoacenaphthylen-1 (2H)-ylideneamino) benzoate,(E4AB) had
been synthesized in good yield by the acid-catalyzed condensation reaction of …

Polycyclic aromatic hydrocarbons are metabolized in vivo resulting in the formation a range
of oxidized products metabolites. The metabolites generated are more water soluable and …

Microbial transformations, including yeast or bacterial or enzymatic biotransformations,
bioconversions, or biodegenerations, have been used since the early days of mankind for …