Next generation sequencing (NGS) combined with bioinformatics has successfully been
used in a vast array of analyses for infectious disease research of public health relevance …

Malaria is a global public health burden with an estimated 229 million cases reported
worldwide in 2019. About 94% of the reported cases were recorded in the African region …

Malaria causes high levels of morbidity and mortality in human beings worldwide. According
to the World Health Organization (WHO), about half a million people die of this disease each …

Fast and effective detection of the causative agent of malaria in humans, protozoan
Plasmodium parasites, is of crucial importance for increasing the effectiveness of treatment …

Millions of people worldwide lie at the risk of parasitic protozoic infections that kill over a
million people each year. The rising inefficacy of conventional therapeutics to combat these …

Human protozoan diseases represent a serious health problem worldwide, affecting mainly
people in social and economic vulnerability. These diseases have attracted little investment …

Multiplicity of infection (MOI), also termed complexity of infection (COI), is defined as the
number of genetically distinct parasite strains co-infecting a single host, which is an …

Background Current malaria control and elimination strategies rely mainly on efficacious
antimalarial drugs. However, drug resistance is a major threat facing malaria control …

Recent developments in molecular biology and genomics have revolutionized biology and
medicine mainly in the developed world. The application of next generation sequencing …

Background As an alternative to PCR methods, LAMP is increasingly being used in the field
of molecular diagnostics. Under isothermal conditions at 65° C, the entire procedure takes …