Imaging calcium in neurons

C Grienberger, A Konnerth - Neuron, 2012 - cell.com
Calcium ions generate versatile intracellular signals that control key functions in all types of
neurons. Imaging calcium in neurons is particularly important because calcium signals exert …

Structural plasticity upon learning: regulation and functions

P Caroni, F Donato, D Muller - Nature Reviews Neuroscience, 2012 - nature.com
Recent studies have provided long-sought evidence that behavioural learning involves
specific synapse gain and elimination processes, which lead to memory traces that influence …

Single-trial neural dynamics are dominated by richly varied movements

S Musall, MT Kaufman, AL Juavinett, S Gluf… - Nature …, 2019 - nature.com
When experts are immersed in a task, do their brains prioritize task-related activity? Most
efforts to understand neural activity during well-learned tasks focus on cognitive …

CaImAn an open source tool for scalable calcium imaging data analysis

A Giovannucci, J Friedrich, P Gunn, J Kalfon, BL Brown… - elife, 2019 - elifesciences.org
Advances in fluorescence microscopy enable monitoring larger brain areas in-vivo with finer
time resolution. The resulting data rates require reproducible analysis pipelines that are …

Distinct contribution of adult-born hippocampal granule cells to context encoding

NB Danielson, P Kaifosh, JD Zaremba, M Lovett-Barron… - Neuron, 2016 - cell.com
Adult-born granule cells (abGCs) have been implicated in cognition and mood; however, it
remains unknown how these cells behave in vivo. Here, we have used two-photon calcium …

[HTML][HTML] Sublayer-specific coding dynamics during spatial navigation and learning in hippocampal area CA1

NB Danielson, JD Zaremba, P Kaifosh, J Bowler… - Neuron, 2016 - cell.com
The mammalian hippocampus is critical for spatial information processing and episodic
memory. Its primary output cells, CA1 pyramidal cells (CA1 PCs), vary in genetics …

Synaptic organization of visual space in primary visual cortex

MF Iacaruso, IT Gasler, SB Hofer - Nature, 2017 - nature.com
How a sensory stimulus is processed and perceived depends on the surrounding sensory
scene. In the visual cortex, contextual signals can be conveyed by an extensive network of …

Alternating sources of perisomatic inhibition during behavior

B Dudok, PM Klein, E Hwaun, BR Lee, Z Yao, O Fong… - Neuron, 2021 - cell.com
Interneurons expressing cholecystokinin (CCK) and parvalbumin (PV) constitute two key
GABAergic controllers of hippocampal pyramidal cell output. Although the temporally …

Cross-modality sharpening of visual cortical processing through layer-1-mediated inhibition and disinhibition

LA Ibrahim, L Mesik, X Ji, Q Fang, H Li, Y Li, B Zingg… - Neuron, 2016 - cell.com
Cross-modality interaction in sensory perception is advantageous for animals' survival. How
cortical sensory processing is cross-modally modulated and what are the underlying neural …

Vasoactive intestinal polypeptide-expressing interneurons in the hippocampus support goal-oriented spatial learning

GF Turi, WK Li, S Chavlis, I Pandi, J O'Hare… - Neuron, 2019 - cell.com
Diverse computations in the neocortex are aided by specialized GABAergic interneurons
(INs), which selectively target other INs. However, much less is known about how these …