ABSTRACT BP 897 is a potent (Ki= 0.92 nM) dopamine D3 receptor compound developed
for the treatment of cocaine abuse and craving. BP 897 has a high selectivity for the …

We have shown previously that prenatal exposure of rats to 0.5 mg/kg/day of methylmercury
(MeHg) produces gender-dependent changes in motor activity in adulthood. In the present …

In the present study we have investigated the neurotoxic effects of the exposure to a low
dose (0.5 mg/kg/day) of methylmercury (MeHg) on the developing nervous system. Pregnant …

Abstract Characterization of the ontogeny of the cerebral dopaminergic system is crucial for
gaining a greater understanding of normal brain development and its alterations in response …

The expression of dopamine D2 and D3 receptors in the developing rat nucleus accumbens
and striatum was examined using quantitative receptor autoradiography. Male Sprague …

Attention deficit hyperactivity disorder is associated with reduced cortical blood flow that is
reversible with exposure to the psychostimulant methylphenidate (MPH). D3 dopamine …

Background It has been reported that dopamine D3 receptor (D3R) knockout mice display
similar ethanol (EtOH) consumption compared to wild types. In addition, studies with D3R …

The effects of environmental novelty on locomotion elicited by an N-methyl-d-aspartate
(NMDA) receptor antagonist,(+) MK-801 hydrogen maleate [(5R, 10S)-(+)-5-methyl-10, 11 …

Aripiprazole is a second-generation antipsychotic that is increasingly being prescribed to
children and adolescents. Despite this trend, little preclinical research has been done on the …

Adenosine and its receptors are, as part of the brain stress response, potential targets for
neuroprotective drugs. We have investigated if the adenosine receptor system affects the …