Decreased abundance of GDNF mRNA transcript in the immature Sertoli cells of cattle in response to protein kinase inhibitor staurosporine

Y Jiang, NN Cai, XX Zhao, WQ Zhu, J Zhang… - Animal reproduction …, 2020 - Elsevier
Sertoli cells (SC) have important functions in spermatogenesis by regulating development of
spermatogenic cells. Glial cell line-derived neurotrophic factor (GDNF) are produced by SC …

Yeast-based systems for tropical disease drug discovery

R Balaña-Fouce, RM Reguera - Expert Opinion on Drug Discovery, 2016 - Taylor & Francis
The term Lneglected tropical diseasesL (NTDs) is coined to identify a diverse group of
communicable diseases caused by various infectious and parasitic agents that affect more …

Discovery of the mechanism of action of novel compounds that target unicellular eukaryotic parasites

D Begolo, C Clayton - … of Parasite Biology: From Metabolism to …, 2016 - Wiley Online Library
In recent years, most new candidate antiparasitic drugs have been found by screening huge
numbers of compounds for their ability to kill parasites, followed by counterscreening for …

[PDF][PDF] Malaysian Journal of Microbiology

LS Husin, G Krishnasamy, MS Azahar, HT Govender… - researchgate.net
Aims: The present study is aimed at taxonomic characterization and isolation of active
compound MS01 from Streptomyces sp. FACC-A032 which exhibited strong …