Mechanisms underpinning the beneficial effects of fluctuating thermal regimes in insect cold tolerance

H Colinet, JP Rinehart, GD Yocum… - Journal of …, 2018 - journals.biologists.com
Insects exposed to low temperature often have high mortality or exhibit sublethal effects. A
growing number of recent studies have shown beneficial effects of exposing insects to …

Metabolomic Studies in Drosophila

JE Cox, CS Thummel, JM Tennessen - Genetics, 2017 - academic.oup.com
Metabolomic analysis provides a powerful new tool for studies of Drosophila physiology.
This approach allows investigators to detect thousands of chemical compounds in a single …

Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome

HA MacMillan, JM Knee, AB Dennis, H Udaka… - Scientific reports, 2016 - nature.com
Cold tolerance is a key determinant of insect distribution and abundance, and thermal
acclimation can strongly influence organismal stress tolerance phenotypes, particularly in …

High temperature, oxygen, and performance: Insights from reptiles and amphibians

EJ Gangloff, RS Telemeco - Integrative and comparative biology, 2018 - academic.oup.com
Much recent theoretical and empirical work has sought to describe the physiological
mechanisms underlying thermal tolerance in animals. Leading hypotheses can be broadly …

The effects of age and dietary restriction on the tissue‐specific metabolome of Drosophila

MJ Laye, VL Tran, DP Jones, P Kapahi… - Aging cell, 2015 - Wiley Online Library
Dietary restriction (DR) is a robust intervention that extends lifespan and slows the onset of
age‐related diseases in diverse organisms. While significant progress has been made in …

Arginine and proline applied as food additives stimulate high freeze tolerance in larvae of Drosophila melanogaster

V Koštál, J Korbelová, R Poupardin… - Journal of …, 2016 - journals.biologists.com
The fruit fly Drosophila melanogaster is an insect of tropical origin. Its larval stage is
evolutionarily adapted for rapid growth and development under warm conditions and shows …

Hormesis-like effect of mild larval crowding on thermotolerance in Drosophila flies

Y Henry, D Renault, H Colinet - Journal of Experimental …, 2018 - journals.biologists.com
Crowding is a complex stress that can affect organisms' physiology, especially through
decreased food quality and accessibility. Here, we evaluated the effect of larval density on …

Uncovering the benefits of fluctuating thermal regimes on cold tolerance of drosophila flies by combined metabolomic and lipidomic approach

H Colinet, D Renault, M Javal, P Berková… - … et Biophysica Acta (BBA …, 2016 - Elsevier
When exposed to constant low temperatures (CLTs), insects often suffer from cumulative
physiological injuries that can severely compromise their fitness and survival. Yet, mortality …

Entometabolomics: applications of modern analytical techniques to insect studies

CJP Snart, ICW Hardy, DA Barrett - … Experimentalis et Applicata, 2015 - Wiley Online Library
Metabolomic analyses can reveal associations between an organism's metabolome and
further aspects of its phenotypic state, an attractive prospect for many life‐sciences …

Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Candida albicans Infection via Activation of Aryl Hydrocarbon Receptor

Z Wang, L Yin, Y Qi, J Zhang, H Zhu… - Frontiers in Microbiology, 2022 - frontiersin.org
Colonization of the intestinal tract by Candida albicans (C. albicans) can lead to invasive
candidiasis. Therefore, a functional intestinal epithelial barrier is critical for protecting …