Despite increasing evidence that physical activity (PA) contributes to brain health in older
individuals, both at the level of brain structure and function, this relationship is not yet well …

Normal aging is associated with cognitive decline and underlying brain dysfunction.
Previous studies concentrated less on brain network changes at a systems level. Our goal …

Aging and mild cognitive impairment (MCI) are accompanied by decline of cognitive
functions. Meanwhile, the most common form of dementia is Alzheimer's disease (AD) …

Background Adults over age 65 represent the fastest growing population in the US. Decline
in cognitive abilities is a hallmark of advanced age and is associated with loss of …

Objective: We have previously demonstrated that aerobic exercise improves upper extremity
motor function concurrent with changes in motor cortical activity using task-based functional …

Higher levels of physical activity (PA) have been linked to better neurocognitive functioning
in many populations. The current study examines the longitudinal association between PA …

Several studies using neuroimaging techniques have established a positive relationship
between physical activity (PA) and brain structure and function in older populations …

Previous work has shown that older adults who evidence increased right inferior frontal
gyrus (IFG) activity during language tasks show decreased sematic verbal fluency …

Resting cerebral blood flow (CBF) decreases with age; however regulatory increases in
hippocampal CBF have been associated with genetic risk (Apolipoprotein E [APOE] ε4 …

The global growth of an aging population is expected to coincide with an increase in aging-
related pathologies, including those related to brain health. Thus, the potential for …