Leishmania major and L. donovani cause cutaneous leishmaniasis and visceral
leishmaniasis, respectively. Available chemotherapies suffer from toxicity, drug-resistance or …

Canine leishmaniosis (CanL) is a zoonotic disease caused by protozoan Leishmania
infantum. Dogs with CanL are often coinfected with tick-borne bacterial pathogens, including …

Background The Ibizan Hound is a canine breed native to the Mediterranean region, where
leishmaniasis is an endemic zoonosis. Several studies indicate a low prevalence of this …

Ethnopharmacological relevance Phoenix dactylifera L.(date palm) seed is widely used in
Arabian traditional medicine to alleviate several health problems including inflammatory …

(1) Background: Leishmaniasis refers to a group of anthropozoonotic diseases caused by
Leishmania. The major chemotherapeutic agent used for its treatment is Glucantime®®, but …

Simple Summary Vector-borne infectious zoonotic diseases are a relevant problem, not only
in veterinary medicine, but also in human medicine. Dogs are considered the main reservoir …

Background Visceral leishmaniasis is a neglected tropical disease affecting millions of
people worldwide. Macrophages serve as the primary host cells for L. donovani, the immune …

The protozoan parasite Leishmania donovani resides within mammalian macrophages and
alters its antigen-presenting functions to negatively regulate host-protective T cell …

Residing obligatorily as amastigotes within the mammalian macrophages, the parasite
Leishmania donovani inflicts the potentially fatal, globally re-emerging disease visceral …

Leishmania parasites mainly infect macrophages and may cause severe
immunopathologies in their host, which are called leishmaniases. In the current work, we …