[HTML][HTML] Marine microbial L-asparaginase: biochemistry, molecular approaches and applications in tumor therapy and in food industry

FI Qeshmi, A Homaei, P Fernandes… - Microbiological Research, 2018 - Elsevier
The marine environment is a rich source of biological and chemical diversity. It covers more
than 70% of the Earth's surface and features a wide diversity of habitats, often displaying …

Strategies to enhance soluble production of heterologous proteins in Escherichia coli

S Falak, M Sajed, N Rashid - Biologia, 2022 - Springer
Escherichia coli is the first choice host for heterologous production of recombinant proteins
with high yield due to its robust and economical growth. However, occasionally recombinant …

Production of a Novel Marine Pseudomonas aeruginosa Recombinant L-Asparaginase: Insight on the Structure and Biochemical Characterization

F Izadpanah Qeshmi, A Homaei, K Khajeh… - Marine …, 2022 - Springer
The present study focused on the cloning, expression, and characterization of L-
asparaginase of marine Pseudomonas aeruginosa HR03 isolated from fish intestine. Thus …

Biochemical characterization of a novel L-asparaginase from Paenibacillus barengoltzii being suitable for acrylamide reduction in potato chips and mooncakes

R Shi, Y Liu, Q Mu, Z Jiang, S Yang - International journal of biological …, 2017 - Elsevier
A novel L-asparaginase gene (PbAsnase) from Paenibaeillus barengoltzii CAU904 was
cloned and expressed in Escherichia coli. The L-asparaginase gene was 1011 bp encoding …

Characterization of a novel and glutaminase-free type II L-asparaginase from Corynebacterium glutamicum and its acrylamide alleviation efficiency in potato chips

H Chi, B Xia, J Shen, X Zhu, Z Lu, F Lu, P Zhu - International Journal of …, 2022 - Elsevier
Type II L-asparaginase as a pivotal enzyme agent has been applied to treating for acute
lymphoblastic leukemia (ALL) and efficient mitigation of acrylamide formed in fried and …

Expression, characterization and cytotoxicity of recombinant l-asparaginase II from Salmonella paratyphi cloned in Escherichia coli

EM Abdullah, MS Khan, IM Aziz, MS Alokail… - International Journal of …, 2024 - Elsevier
L-asparaginase is a remarkable antineoplastic enzyme used in medicine for the treatment of
acute lymphoblastic leukemia (ALL) as well as in food industries. In this work, the L …

L-Asparaginase from Penicillium sizovae Produced by a Recombinant Komagataella phaffii Strain

M Freitas, P Souza, M Homem-de-Mello… - Pharmaceuticals, 2022 - mdpi.com
L-asparaginase is an important enzyme in the pharmaceutical field used as treatment for
acute lymphoblastic leukemia due to its ability to hydrolyze L-asparagine, an essential …

Insights into the microbial L-asparaginases: from production to practical applications

D Sharma, K Singh, K Singh… - Current Protein and …, 2019 - ingentaconnect.com
L-asparaginase is a valuable protein therapeutic drug utilized for the treatment of leukemia
and lymphomas. Administration of asparaginase leads to asparagine starvation causing …

Recent development in the uses of asparaginase as food enzyme

S Alam, K Pranaw, R Tiwari, SK Khare - Green bio-processes: enzymes in …, 2019 - Springer
Abstract Asparaginase (EC 3.5. 1.1), an important enzyme, is broadly disseminated in all the
three domains of life and responsible for catalysing conversion of asparagine into aspartic …

An integrative, multiparametric approach for the comprehensive assessment of microbial quality and pollution in aquaculture systems

L Stabili, M Di Salvo, P Alifano, A Talà - Microbial ecology, 2022 - Springer
As the aquaculture sector significantly expanded worldwide in the past decades, the concept
of sustainable aquaculture has developed with the challenge of not only maximizing benefits …