Proprotein convertase subtilisin-like kexin type 9 (PCSK9) is a newly discovered serine
protease that destroys low density lipoprotein (LDL) receptors in liver and thereby controls …

Autosomal dominant hypercholesterolemia (ADH) is characterized by isolated elevation of
plasmatic low‐density lipoprotein cholesterol associated with high risk of premature …

Genetic studies have demonstrated an important role for proprotein convertase
subtilisin/kexin type 9 (PCSK9) as a determinant of plasma cholesterol levels. However, the …

The purpose of this manuscript is to highlight the peculiarities of the Mexican population
regarding the clinical expression, genetics, and treatment of lipid disorders. Furthermore, it is …

Background There is little information about familial hypercholesterolemia (FH)
epidemiology and care in Ibero-American countries. The Ibero-American FH network aims at …

Atherosclerotic cardiovascular disease (ASCVD) affects more than 1 in 3 American adults.
Hypercholesterolemia is a major treatable risk factor for ASCVD, yet many individuals fail to …

Background—Autosomal dominant hypercholesterolemia (ADH), characterized by elevated
plasma levels of low-density lipoprotein (LDL)-cholesterol, is caused by variants in at least 3 …

The burden caused by familial hypercholesterolemia (FH) varies among countries and
ethnic groups. The prevalence and characteristics of FH in Latin American (LA) countries is …

Familial hypercholesterolaemia (FH) is caused by mutations in lipid metabolism genes,
predominantly in low-density lipoprotein receptor (LDLR), apolipoprotein B (APOB) …

BACKGROUND/PURPOSE: Autosomal dominant hypercholesterolemia (ADH) is an
autosomal dominant inherited disease characterized by an increase in low-density …