Mitochondrial functionality in male fertility: from spermatogenesis to fertilization

YJ Park, MG Pang - Antioxidants, 2021 - mdpi.com
Mitochondria are structurally and functionally distinct organelles that produce adenosine
triphosphate (ATP) through oxidative phosphorylation (OXPHOS), to provide energy to …

Unraveling the harmful effect of oxidative stress on male fertility: A mechanistic insight

T Hussain, M Kandeel, E Metwally, G Murtaza… - Frontiers in …, 2023 - frontiersin.org
Male infertility is a widely debated issue that affects males globally. There are several
mechanisms involved. Oxidative stress is accepted to be the main contributing factor, with …

Calcium channels in the development, maturation, and function of spermatozoa

A Darszon, T Nishigaki, C Beltran… - Physiological …, 2011 - journals.physiology.org
A proper dialogue between spermatozoa and the egg is essential for conception of a new
individual in sexually reproducing animals. Ca2+ is crucial in orchestrating this unique event …

From sperm motility to sperm-borne microRNA signatures: new approaches to predict male fertility potential

MBR Alves, ECC Celeghini… - Frontiers in Cell and …, 2020 - frontiersin.org
In addition to the paternal genome, spermatozoa carry several intrinsic factors, including
organelles (eg, centrioles and mitochondria) and molecules (eg, proteins and RNAs), which …

Proteomic landscape of seminal plasma associated with dairy bull fertility

AGA Viana, AMA Martins, AH Pontes, W Fontes… - Scientific Reports, 2018 - nature.com
Male fertility is the ability of sperm to fertilize the egg and sustain embryo development.
Several factors determine the fertilizing capacity of mammalian sperm, including those …

Epigenetic disorders and altered gene expression after use of assisted reproductive technologies in domestic cattle

R Urrego, N Rodriguez-Osorio, H Niemann - Epigenetics, 2014 - Taylor & Francis
The use of Assisted Reproductive Technologies (ARTs) in modern cattle breeding is an
important tool for improving the production of dairy and beef cattle. A frequently employed …

Small RNA sequencing of cryopreserved semen from single bull revealed altered miRNAs and piRNAs expression between High-and Low-motile sperm populations

E Capra, F Turri, B Lazzari, P Cremonesi, TM Gliozzi… - BMC genomics, 2017 - Springer
Abstract Background Small RNAs present in bovine ejaculate can be linked to sperm
abnormalities and fertility disorders. At present, quality parameters routinely used in semen …

Male fertility status is associated with DNA methylation signatures in sperm and transcriptomic profiles of bovine preimplantation embryos

J Kropp, JA Carrillo, H Namous, A Daniels, SM Salih… - BMC genomics, 2017 - Springer
Background Infertility in dairy cattle is a concern where reduced fertilization rates and high
embryonic loss are contributing factors. Studies of the paternal contribution to reproductive …

Metabolomic markers of fertility in bull seminal plasma

ALC Velho, E Menezes, T Dinh, A Kaya, E Topper… - PLoS …, 2018 - journals.plos.org
Metabolites play essential roles in biological systems, but detailed identities and
significance of the seminal plasma metabolome related to bull fertility are still unknown. The …

Sperm protamine-status correlates to the fertility of breeding bulls

S Dogan, P Vargovic, R Oliveira, LE Belser… - Biology of …, 2015 - academic.oup.com
During fertilization, spermatozoa make essential contributions to embryo development by
providing oocyte activating factors, centrosomal components, and paternal chromosomes …