The Runt‐related transcription factors (RUNX) belong to an ancient family of metazoan
genes involved in developmental processes. Through multiple protein‐interacting partners …

The study of RUNX3 in tumor pathogenesis is a rapidly expanding area of cancer research.
Functional inactivation of RUNX3—through mutation, epigenetic silencing, or cytoplasmic …

IGHV polymorphism provides a rich source of humoral immune system diversity. One
important example is the IGHV1-69 germline gene where the biased use of alleles that …

Immunoactinopathies caused by mutations in actin‐related proteins are a growing group of
inborn errors of immunity (IEI). Immunoactinopathies are caused by a dysregulated actin …

Metastasis remains the major driver of mortality in patients with cancer. The multistep
metastatic process starts with the dissemination of tumor cells from a primary site and …

Runx2 is best known as an essential factor in osteoblast differentiation and bone
development but, like many other transcription factors involved in development, is known to …

The transcription factor Runx3 is highly expressed in CD8+ T and NK cytotoxic lymphocytes
and is required for their effective activation and proliferation but molecular insights into the …

Transcription factors induced by the LH surge play a vital role in reprogramming the gene
expression in periovulatory follicles. The present study investigated the role of RUNX2 …

ChIP-seq performed on lymphoblastoid cell lines (LCLs), expressing epitope-tagged
EBNA3A, EBNA3B or EBNA3C from EBV-recombinants, revealed important principles of …

Previous linkage studies have identified a region at 1p36 as the susceptibility locus (IBD7) of
inflammatory bowel disease (IBD). The objective of this study was to investigate whether …