Suprachiasmatic nucleus: cell autonomy and network properties

DK Welsh, JS Takahashi, SA Kay - Annual review of physiology, 2010 - annualreviews.org
The suprachiasmatic nucleus (SCN) is the primary circadian pacemaker in mammals.
Individual SCN neurons in dispersed culture can generate independent circadian …

The suprachiasmatic nucleus at 50: looking back, then looking forward

D Ono, DR Weaver, MH Hastings… - Journal of biological …, 2024 - journals.sagepub.com
It has been 50 years since the suprachiasmatic nucleus (SCN) was first identified as the
central circadian clock and 25 years since the last overview of developments in the field was …

The development of regulatory functions from birth to 5 years: Insights from premature infants

R Feldman - Child development, 2009 - Wiley Online Library
This study examined physiological, emotional, and attentional regulatory functions as
predictors of self‐regulation in 125 infants followed 7 times from birth to 5 years …

Intrinsic, nondeterministic circadian rhythm generation in identified mammalian neurons

AB Webb, N Angelo, JE Huettner… - Proceedings of the …, 2009 - National Acad Sciences
Circadian rhythms are modeled as reliable and self-sustained oscillations generated by
single cells. The mammalian suprachiasmatic nucleus (SCN) keeps near 24-h time in vivo …

Emergence of noise-induced oscillations in the central circadian pacemaker

CH Ko, YR Yamada, DK Welsh, ED Buhr, AC Liu… - PLoS …, 2010 - journals.plos.org
Bmal1 is an essential transcriptional activator within the mammalian circadian clock. We
report here that the suprachiasmatic nucleus (SCN) of Bmal1-null mutant mice …

Synchronization-induced rhythmicity of circadian oscillators in the suprachiasmatic nucleus

S Bernard, D Gonze, B Čajavec, H Herzel… - PLoS computational …, 2007 - journals.plos.org
The suprachiasmatic nuclei (SCN) host a robust, self-sustained circadian pacemaker that
coordinates physiological rhythms with the daily changes in the environment. Neuronal …

Mathematical modeling of circadian rhythms

A Asgari‐Targhi, EB Klerman - Wiley Interdisciplinary Reviews …, 2019 - Wiley Online Library
Circadian rhythms are endogenous~ 24‐hr oscillations usually entrained to daily
environmental cycles of light/dark. Many biological processes and physiological functions …

Gonadectomy reveals sex differences in circadian rhythms and suprachiasmatic nucleus androgen receptors in mice

E Iwahana, I Karatsoreos, S Shibata, R Silver - Hormones and behavior, 2008 - Elsevier
In mammals, it is well established that circadian rhythms in physiology and behavior,
including the rhythmic secretion of hormones, are regulated by a brain clock located in the …

Exploring spatiotemporal organization of SCN circuits

L Yan, I Karatsoreos, J LeSauter… - Cold Spring Harbor …, 2007 - symposium.cshlp.org
Suprachiasmatic nucleus (SCN) neuroanatomy has been a subject of intense interest since
the discovery of the SCN's function as a brain clock and subsequent studies revealing …

Socially synchronized circadian oscillators

G Bloch, ED Herzog, JD Levine… - Proceedings of the …, 2013 - royalsocietypublishing.org
Daily rhythms of physiology and behaviour are governed by an endogenous timekeeping
mechanism (a circadian 'clock'). The alternation of environmental light and darkness …