Three decades of nanopore sequencing

D Deamer, M Akeson, D Branton - Nature biotechnology, 2016 - nature.com
A long-held goal in sequencing has been to use a voltage-biased nanoscale pore in a
membrane to measure the passage of a linear, single-stranded (ss) DNA or RNA molecule …

Nanopore analytics: sensing of single molecules

S Howorka, Z Siwy - Chemical Society Reviews, 2009 - pubs.rsc.org
In nanopore analytics, individual molecules pass through a single nanopore giving rise to
detectable temporary blockades in ionic pore current. Reflecting its simplicity, nanopore …

Transmitter and receiver architectures for molecular communications: A survey on physical design with modulation, coding, and detection techniques

M Kuscu, E Dinc, BA Bilgin, H Ramezani… - Proceedings of the …, 2019 - ieeexplore.ieee.org
Inspired by nature, molecular communications (MC), ie, the use of molecules to encode,
transmit, and receive information, stands as the most promising communication paradigm to …

Single-nucleotide discrimination in immobilized DNA oligonucleotides with a biological nanopore

D Stoddart, AJ Heron, E Mikhailova… - Proceedings of the …, 2009 - National Acad Sciences
The sequencing of individual DNA strands with nanopores is under investigation as a rapid,
low-cost platform in which bases are identified in order as the DNA strand is transported …

Membrane protein structure, function, and dynamics: a perspective from experiments and theory

Z Cournia, TW Allen, I Andricioaei, B Antonny… - The Journal of …, 2015 - Springer
Membrane proteins mediate processes that are fundamental for the flourishing of biological
cells. Membrane-embedded transporters move ions and larger solutes across membranes; …

[图书][B] Polymer translocation

M Muthukumar - 2016 - books.google.com
A reflection of the significant advances in the field, this book discusses the macromolecular
basis of polymer translocation that have emerged based on experimentation, new models …

Rapid fabrication of uniformly sized nanopores and nanopore arrays for parallel DNA analysis

MJ Kim, M Wanunu, DC Bell, A Meller - Advanced materials, 2006 - Wiley Online Library
Nanometer-sized pores can be used to detect and characterize biopolymers, such as DNA,
RNA, and polypeptides, with single-molecule resolution. Experiments performed with the 1.5 …

Colloquium: Physical approaches to DNA sequencing and detection

M Zwolak, M Di Ventra - Reviews of Modern Physics, 2008 - APS
With the continued improvement of sequencing technologies, the prospect of genome-based
medicine is now at the forefront of scientific research. To realize this potential, however, a …

Chemically modified solid-state nanopores

M Wanunu, A Meller - Nano letters, 2007 - ACS Publications
Nanopores are extremely sensitive single-molecule sensors. Recently, electron beams have
been used to fabricate synthetic nanopores in thin solid-state membranes with …

Enhanced translocation of single DNA molecules through α-hemolysin nanopores by manipulation of internal charge

G Maglia, MR Restrepo… - Proceedings of the …, 2008 - National Acad Sciences
Both protein and solid-state nanopores are under intense investigation for the analysis of
nucleic acids. A crucial advantage of protein nanopores is that site-directed mutagenesis …