miRNAs in lung cancer. A systematic review identifies predictive and prognostic miRNA candidates for precision medicine in lung cancer

S Zhong, H Golpon, P Zardo, J Borlak - Translational Research, 2021 - Elsevier
Lung cancer (LC) is the leading cause of cancer-related death worldwide and miRNAs play
a key role in LC development. To better diagnose LC and to predict drug treatment …

MiRNAs in lung adenocarcinoma: role, diagnosis, prognosis, and therapy

Y Song, L Kelava, I Kiss - International Journal of Molecular Sciences, 2023 - mdpi.com
Lung cancer has emerged as a significant public health challenge and remains the leading
cause of cancer-related mortality worldwide. Among various types of lung malignancies …

Circulating miR-16-5p, miR-92a-3p, and miR-451a in plasma from lung cancer patients: potential application in early detection and a regulatory role in tumorigenesis …

PP Reis, SA Drigo, RF Carvalho, RM Lopez Lapa… - Cancers, 2020 - mdpi.com
Background: Micro (mi) RNAs, potent gene expression regulators associated with
tumorigenesis, are stable, abundant circulating molecules, and detectable in plasma. Thus …

The impact of air pollution exposure on the MicroRNA machinery and lung cancer development

M Sima, A Rossnerova, Z Simova… - Journal of Personalized …, 2021 - mdpi.com
Small non-coding RNA molecules (miRNAs) play an important role in the epigenetic
regulation of gene expression. As these molecules have been repeatedly implicated in …

Progress of endogenous and exogenous nanoparticles for cancer therapy and diagnostics

H Fujita, S Ohta, N Nakamura, M Somiya, M Horie - Genes, 2023 - mdpi.com
The focus of this brief review is to describe the application of nanoparticles, including
endogenous nanoparticles (eg, extracellular vesicles, EVs, and virus capsids) and …

Circulating microRNA biomarkers for lung cancer detection in East Asian populations

H Yu, Z Guan, K Cuk, Y Zhang, H Brenner - Cancers, 2019 - mdpi.com
Background: Lung cancer (LC) is the leading cause of cancer-related death in Eastern Asia.
The prognosis of LC highly depends on tumor stages and early detection could substantially …

[HTML][HTML] MiR-486 as an effective biomarker in cancer diagnosis and prognosis: a systematic review and meta-analysis

M Jiang, X Li, X Quan, X Yang, C Zheng, X Hao, R Qu… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Purpose MiR-486 was found to be associated with cancer's diagnosis and prognosis. This
meta-analysis aimed to investigate the potential effect of miR-486 on cancer detection and …

Clinically Correlated MicroRNAs in the Diagnosis of Non‐Small Cell Lung Cancer: A Systematic Review and Meta‐Analysis

M Jiang, X Li, X Quan, X Li… - BioMed Research …, 2018 - Wiley Online Library
(1) Background. Non‐small cell lung cancer (NSCLC) has a high mortality rate. MiRNAs
have been found to be diagnostic biomarkers for NSCLC. However, controversial results …

Hsa-let-7c exerts an anti-tumor function by negatively regulating ANP32E in lung adenocarcinoma

L Wang, J Li, Y Li, LB Pang - Tissue and Cell, 2020 - Elsevier
We attempted to investigate the relationship between hsa-let-7c and ANP32E, as well as
their influence on the cells phenotype of lung adenocarcinoma. Expression of hsa-let-7c and …

A new function for miRNAs as regulators of autophagy

F Aredia, AI Scovassi - Future Medicinal Chemistry, 2017 - Taylor & Francis
Autophagy is a self-digestive process regulated by an intricate network of factors able either
to ensure the prosurvival function of autophagy or to convert it in a death pathway. Recently …