In this review, we summarize recent work on the “green synthesis” of carbon nanoparticles
(CNPs) and their application with a focus on biomedical applications. Recent developments …

The endoplasmic reticulum (ER) employs a diverse proteome landscape to orchestrate
many cellular functions, ranging from protein and lipid synthesis to calcium ion flux and inter …

Here, we describe a novel approach that allows pathologists to three-dimensionally analyse
malignant tissues, including the tumour-host tissue interface. Our visualization technique …

Correlative light and electron cryo-microscopy (cryo-CLEM) combines information from the
specific labeling of fluorescence cryo-microscopy (cryo-FM) with the high resolution in …

Cryo-electron microscopy (cryo-EM) is a powerful tool for macromolecular to near-atomic
resolution structure determination in the biological sciences. The specimen is maintained in …

Cryo-correlative light and electron microscopy (CLEM) is a technique that uses the
spatiotemporal cues from fluorescence light microscopy (FLM) to investigate the high …

The endoplasmic reticulum (ER) is a highly dynamic network of membranes. Here, we
combine live-cell microscopy with in situ cryo–electron tomography to directly visualize ER …

The signaling network of the unfolded protein response (UPR) adjusts the protein-folding
capacity of the endoplasmic reticulum (ER) according to need. The most conserved UPR …

Electron microscopy has been instrumental in our understanding of complex biological
systems. Although electron microscopy reveals cellular morphology with nanoscale …

Characterizing relationships between Zn2+, insulin, and insulin vesicles is of vital
importance to the study of pancreatic beta cells. However, the precise content of Zn2+ and …