Bioactive aurones, indanones, and other hemiindigoid scaffolds: medicinal chemistry and photopharmacology perspectives
LM Lazinski, G Royal, M Robin… - Journal of Medicinal …, 2022 - ACS Publications
Hemiindigoids comprise a range of natural and synthetic scaffolds that share the same
aromatic hydrocarbon backbone as well as promising biological and optical properties. The …
aromatic hydrocarbon backbone as well as promising biological and optical properties. The …
Journey on naphthoquinone and anthraquinone derivatives: new insights in Alzheimer's disease
M Campora, V Francesconi, S Schenone, B Tasso… - Pharmaceuticals, 2021 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease that is characterized
by memory loss, cognitive impairment, and functional decline leading to dementia and …
by memory loss, cognitive impairment, and functional decline leading to dementia and …
Vitamin k3 inhibits protein aggregation: implication in the treatment of amyloid diseases
Protein misfolding and aggregation have been associated with several human diseases
such as Alzheimer's, Parkinson's and familial amyloid polyneuropathy etc. In this study, anti …
such as Alzheimer's, Parkinson's and familial amyloid polyneuropathy etc. In this study, anti …
The role of phytochemicals as micronutrients in health and disease
MJR Howes, MSJ Simmonds - Current Opinion in Clinical …, 2014 - journals.lww.com
Evidence for the role of phytochemicals in health and disease is growing, but associations
between phytochemicals and disease need to be more firmly understood and established …
between phytochemicals and disease need to be more firmly understood and established …
Network pharmacology-based study on the mechanism of action for herbal medicines in Alzheimer treatment
Ethnopharmacological relevance Alzheimer's disease (AD), as the most common type of
dementia, has brought a heavy economic burden to healthcare system around the world …
dementia, has brought a heavy economic burden to healthcare system around the world …
On the role of synthesized hydroxylated chalcones as dual functional amyloid-β aggregation and ferroptosis inhibitors for potential treatment of Alzheimer's disease
In addition to amyloid cascade hypothesis, ferroptosis–a recently identified cell death
pathway associated with the accumulation of lipid hydroperoxides–was hypothesized as …
pathway associated with the accumulation of lipid hydroperoxides–was hypothesized as …
Photosensitizing materials and platforms for light-triggered modulation of Alzheimer's β-amyloid self-assembly
The abnormal aggregation of β-amyloid (Aβ) peptides is a hallmark of Alzheimer's disease
(AD) that affects more than 10% of the people over the age 60 world-wide. While the exact …
(AD) that affects more than 10% of the people over the age 60 world-wide. While the exact …
Recent advances in the design and applications of amyloid-β peptide aggregation inhibitors for Alzheimer's disease therapy
Alzheimer's disease (AD) is an irreversible neurological disorder that progresses gradually
and can cause severe cognitive and behavioral impairments. This disease is currently …
and can cause severe cognitive and behavioral impairments. This disease is currently …
Olive biophenols reduces alzheimer's pathology in SH-SY5Y cells and APPswe mice
Alzheimer's disease (AD) is a major neurodegenerative disease, associated with the
hallmark proteinacious constituent called amyloid beta (Aβ) of senile plaques. Moreover, it is …
hallmark proteinacious constituent called amyloid beta (Aβ) of senile plaques. Moreover, it is …
Inhibition of Aβ aggregates in Alzheimer's disease by epigallocatechin and epicatechin-3-gallate from green tea
T Chen, Y Yang, S Zhu, Y Lu, L Zhu, Y Wang… - Bioorganic …, 2020 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
accumulation of senile plaques, which are primarily composed of misfolded amyloid β …
accumulation of senile plaques, which are primarily composed of misfolded amyloid β …