Severe traumatic brain injury remains a major health-care problem worldwide. Although major progress has been made in understanding of the pathophysiology of this injury, this …
Y Zhang, M Chopp, Y Meng, M Katakowski, H Xin… - Journal of …, 2015 - thejns.org
OBJECT Transplanted multipotent mesenchymal stromal cells (MSCs) improve functional recovery in rats after traumatic brain injury (TBI). In this study the authors tested a novel …
Y Zhang, M Chopp, ZG Zhang, M Katakowski… - Neurochemistry …, 2017 - Elsevier
Multipotent human bone marrow derived mesenchymal stem cells (hMSCs) improve functional outcome after experimental traumatic brain injury (TBI). The present study was …
H Ni, S Yang, F Siaw-Debrah, J Hu, K Wu… - Frontiers in …, 2019 - frontiersin.org
Traumatic brain injury (TBI) is a leading cause of mortality and disability worldwide. Although treatment guidelines have been developed, no best treatment option or medicine for this …
Diffusion tensor imaging is highly sensitive to the microstructural integrity of the brain and has uncovered significant abnormalities following traumatic brain injury not appreciated …
Y Yang, Y Ye, X Su, J He, W Bai, X He - Frontiers in cellular …, 2017 - frontiersin.org
Exosomes are endosomal origin membrane-enclosed small vesicles (30–100 nm) that contain various molecular constituents including proteins, lipids, mRNAs and microRNAs …
SI Savitz, V Misra, M Kasam, H Juneja… - Annals of …, 2011 - Wiley Online Library
Objective: Cellular therapy is an investigational approach for stroke. Mononuclear cells (MNCs) from the bone marrow reduce neurological deficits in animal stroke models. We …
K Min, J Song, JY Kang, J Ko, JS Ryu, MS Kang… - Stem Cells, 2013 - academic.oup.com
Allogeneic umbilical cord blood (UCB) has therapeutic potential for cerebral palsy (CP). Concomitant administration of recombinant human erythropoietin (rhEPO) may boost the …
C Grochowski, E Radzikowska… - Clinical neurology and …, 2018 - Elsevier
Adult mammalian neural stem cells are unique because of their properties, such as differentiation capacity, self-renewal, quiescence, and also because they exist in specific …