Duchenne muscular dystrophy (DMD) is a severe, progressive, and ultimately fatal disease
of skeletal muscle wasting, respiratory insufficiency, and cardiomyopathy. The identification …

Currently, there is no completely effective therapy available for metastatic
phaeochromocytomas (PCCs) and paragangliomas. In this study, we explore new molecular …

Breakthrough technologies to measure cellular oxygen consumption and proton efflux are
reigniting the study of cellular energetics by increasing the scope and pace with which …

Background Muscle wasting and weakness in Duchenne muscular dystrophy (DMD) causes
severe locomotor limitations and early death due in part to respiratory muscle failure. Given …

Skeletal muscle possesses remarkable plasticity that permits functional adaptations to a
wide range of signals such as motor input, exercise, and disease. Small animal models have …

A growing body of research is investigating the potential contribution of mitochondrial
function to the etiology of type 2 diabetes. Numerous in vitro, in situ, and in vivo …

Background Although mounting evidence indicates that insulin resistance (IR) co‐occurs
with mitochondrial dysfunction in skeletal muscle, there is no clear causal link between …

Mitochondrial stress may be a secondary contributor to muscle weakness in inherited
muscular dystrophies. Duchenne muscular dystrophy has received the majority of attention …

Abstract Duchenne Muscular Dystrophy (DMD) is a fatal neuromuscular disease that is
characterised by dystrophin-deficiency and chronic Ca 2+-induced skeletal muscle wasting …

Duchenne Muscular Dystrophy is a chronic, progressive and ultimately fatal skeletal muscle
wasting disease characterised by sarcolemmal fragility and intracellular Ca2+ dysregulation …