To date, the only Neandertal genome that has been sequenced to high quality is from an
individual found in Southern Siberia. We sequenced the genome of a female Neandertal …

Background Recent randomised trials showed benefit for anti-inflammatory therapies in
coronary disease but excluded stroke. The prognostic value of blood inflammatory markers …

Background and purpose Stroke is the leading cause of mortality and disability in China.
Precise aetiological classification, imaging and biological markers may predict the prognosis …

Frontotemporal dementia (FTD), dementia with Lewy bodies (DLB) and vascular dementia
(VaD) are the most common forms of dementia after Alzheimer's disease (AD). The …

Background and Purpose: Stroke is a complex disease with multiple genetic and
environmental risk factors. Blacks endure a nearly 2-fold greater risk of stroke and are 2× to …

Background and aims Elevated fibrinogen levels have been observed in patients with acute
ischemic stroke, but the association of fibrinogen with stroke outcomes is still undefined. We …

Background Stroke-associated pneumonia (SAP) is a serious and common complication in
stroke patients. Purpose We aimed to develop and validate an easy-to-use model for …

Objective: We related a panel of inflammatory biomarkers to risk of incident ischemic stroke
(IIS) in a community-dwelling sample. Methods: Stroke-free Framingham offspring attending …

Epigenetic modifications are hereditable and modifiable factors that do not alter the DNA
sequence. These epigenetic factors include DNA methylation, acetylation of histones and …

Background and Purpose—Vascular recurrence occurs in 11% of patients during the first
year after ischemic stroke (IS) or transient ischemic attack. Clinical scores do not predict the …