In 2017–2019, the March of Dimes convened a workgroup with biomedical, clinical, and
epidemiologic expertise to review knowledge of the causes of the persistent Black-White …

Despite considerable effort aimed at decreasing the incidence of spontaneous preterm birth,
it remains the leading cause of perinatal morbidity and mortality. Screening strategies are …

Abstract In1998, the Boston Birth Cohort (BBC) was initiated at Boston Medical Center
(BMC) in response to persistently high rates of preterm birth (PTB, defined as birth before 37 …

Background Advanced biological aging, as measured by epigenetic aging indices, is
associated with early mortality and morbidity. Associations between maternal epigenetic …

Preterm birth (PTB), defined as the birth of a child before 37 completed weeks gestation,
affects approximately 11% of live births and is the leading cause of death in children under 5 …

Abstract Although Black American mothers and infants are at higher risk for morbidity and
mortality than their White counterparts, the biological mechanisms underlying these …

Placental vascularization is a tightly regulated physiological process in which the maternal
immune system plays a fundamental role. Vascularization of the maternal-placental interface …

Background Preterm birth, defined as parturition before 37 completed weeks of gestation, is
associated with an increased risk of neonatal complications and death, as well as poor …

Preterm birth (PTB) is a major public health challenge, and novel, sensitive approaches to
predict PTB are still evolving. Epigenomic markers are being explored as biomarkers of PTB …

Preterm birth is the major cause of newborn and infant mortality affecting nearly one in every
ten live births. The current study was designed to develop an epigenetic biomarker for …