The accumulation of misfolded proteins in the human brain is one of the critical features of
many neurodegenerative diseases, including Alzheimer's disease (AD). Assembles of beta …

The misfolding of the cellular prion protein (PrP C) causes fatal neurodegenerative
diseases. Yet PrP C is highly conserved in mammals, suggesting that it exerts beneficial …

Prions are unprecedented infectious pathogens that cause a group of invariably fatal
neurodegenerative diseases by an entirely novel mechanism. Prion diseases may present …

▪ Abstract Prion diseases are transmissible neurodegenerative conditions that include
Creutzfeldt-Jakob disease (CJD) in humans and bovine spongiform encephalopathy (BSE) …

THE'protein only'hypothesis1 states that a modified form of normal prion protein triggers
infectious neurodegenerative diseases, such as bovine spongiform encephalopathy (BSE) …

The prion protein, PrPC, is a small, cell-surface glycoprotein notable primarily for its critical
role in pathogenesis of the neurodegenerative disorders known as prion diseases. A …

Prion Protein Biology: Cell Skip to Main Content Advertisement Cell This journal offers authors
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The cellular uptake and intracellular distribution of the essential but highly toxic nutrient,
copper, is a precisely orchestrated process. Copper homeostasis is coordinated by several …

In our daily life, we are exposed to uncontrollable and stressful events that disrupt our sleep.
However, the underlying neural mechanisms deteriorating the quality of non-rapid eye …

Prion diseases are transmissible spongiform encephalopathies (TSEs), attributed to
conformational conversion of the cellular prion protein (PrPC) into an abnormal conformer …