[HTML][HTML] Roles and mechanisms of renalase in cardiovascular disease: A promising therapeutic target

Y Li, W Wu, W Liu, M Zhou - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Cardiovascular disease (CVD) is prevalent worldwide and remains a leading cause of
death. Although substantial progress has been made in the diagnosis and treatment of CVD …

[HTML][HTML] Proximal nephron

JL Zhuo, XC Li - Comprehensive Physiology, 2013 - ncbi.nlm.nih.gov
The kidney plays a fundamental role in maintaining body salt and fluid balance and blood
pressure homeostasis through the actions of its proximal and distal tubular segments of …

Human renalase: a review of its biology, function, and implications for hypertension

GV Desir, L Wang, AJ Peixoto - Journal of the American Society of …, 2012 - Elsevier
Renalase is a novel flavoprotein, highly expressed in kidney and heart, which metabolizes
catecholamines and catecholamine-like substances via a superoxide (O2–)-dependent …

Renalase protects against ischemic AKI

HT Lee, JY Kim, M Kim, P Wang, L Tang… - Journal of the …, 2013 - journals.lww.com
Elevated levels of plasma catecholamines accompany ischemic AKI, possibly contributing
the inflammatory response. Renalase, an amine oxidase secreted by the proximal tubule …

Renalase in hypertension and kidney disease

GV Desir, AJ Peixoto - Nephrology dialysis transplantation, 2014 - academic.oup.com
Renalase, a recently discovered flavoprotein, which is strongly expressed in the kidney and
heart, effectively metabolizes catecholamines. It was discovered during the search to identify …

Proteomic Basis of Stress Responses in the Gills of the Pacific Oyster Crassostrea gigas

Y Zhang, J Sun, H Mu, J Li, Y Zhang, F Xu… - Journal of proteome …, 2015 - ACS Publications
The Pacific oyster Crassostrea gigas is one of the dominant sessile inhabitants of the
estuarine intertidal zone, which is a physically harsh environment due to the presence of a …

Therapeutic perspectives in hypertension: novel means for renin–angiotensin–aldosterone system modulation and emerging device-based approaches

T Unger, L Paulis, DA Sica - European heart journal, 2011 - academic.oup.com
The conventional antihypertensive therapies including renin–angiotensin–aldosterone
system antagonists (converting enzyme inhibitors, receptor blockers, renin inhibitors, and …

Exercise differentially regulates renalase expression in skeletal muscle and kidney

B Czarkowska-Paczek… - The Tohoku Journal of …, 2013 - jstage.jst.go.jp
Renalase is a newly discovered amine oxidase and may lower blood pressure by
metabolizing catecholamines. We have hypothesized that exercise and training may …

Potential impact of microRNA gene polymorphisms in the pathogenesis of diabetes and atherosclerotic cardiovascular disease

I Elfaki, R Mir, MM Mir, FM AbuDuhier… - Journal of personalized …, 2019 - mdpi.com
MicroRNAs (miRNAs) are endogenous, small (18–23 nucleotides), non-coding RNA
molecules. They regulate the posttranscriptional expression of their target genes. MiRNAs …

Renalase gene polymorphisms in patients with type 2 diabetes, hypertension and stroke

M Buraczynska, P Zukowski, K Buraczynska… - Neuromolecular …, 2011 - Springer
Renalase is a novel, recently identified, flavin adenine dinucleotide-dependent amine
oxidase. It is secreted by the kidney and metabolizes circulating catecholamines. Renalase …