[HTML][HTML] On a highway to the brain: A review on nose-to-brain drug delivery using nanoparticles

ML Formica, DA Real, ML Picchio, E Catlin… - Applied Materials …, 2022 - Elsevier
The administration of drugs to the central nervous system (CNS) is primarily controlled by
the blood-brain barrier (BBB), a structure that prevents the passage of foreign compounds …

Chitosan-based (Nano) materials for novel biomedical applications

G Kravanja, M Primožič, Ž Knez, M Leitgeb - Molecules, 2019 - mdpi.com
Chitosan-based nanomaterials have attracted significant attention in the biomedical field
because of their unique biodegradable, biocompatible, non-toxic, and antimicrobial nature …

Preparation and applications of chitosan and cellulose composite materials

TG Ambaye, M Vaccari, S Prasad… - Journal of …, 2022 - Elsevier
Chitosan is a natural fiber, chemically cellulose-like biopolymer, which is processed from
chitin. Its use as a natural polymer is getting more attention because it is non-toxic …

Multiple roles of chitosan in mucosal drug delivery: an updated review

P Mura, F Maestrelli, M Cirri, N Mennini - Marine Drugs, 2022 - mdpi.com
Chitosan (CS) is a linear polysaccharide obtained by the deacetylation of chitin, which, after
cellulose, is the second biopolymer most abundant in nature, being the primary component …

Chitosan as a coating material for nanoparticles intended for biomedical applications

LA Frank, GR Onzi, AS Morawski, AR Pohlmann… - Reactive and Functional …, 2020 - Elsevier
This review provides a comprehensive and updated overview of the state of the art related to
the biomedical applications of nanoparticles coated with chitosan. Discussions were based …

[HTML][HTML] Nanosystems for the encapsulation of natural products: The case of chitosan biopolymer as a matrix

A Detsi, E Kavetsou, I Kostopoulou, I Pitterou… - Pharmaceutics, 2020 - mdpi.com
Chitosan is a cationic natural polysaccharide, which has emerged as an increasingly
interesting biomaterialover the past few years. It constitutes a novel perspective in drug …

The design of poly (lactide-co-glycolide) nanocarriers for medical applications

D Essa, PPD Kondiah, YE Choonara… - … in bioengineering and …, 2020 - frontiersin.org
Polymeric biomaterials have found widespread applications in nanomedicine, and poly
(lactide-co-glycolide),(PLGA) in particular has been successfully implemented in numerous …

Brain targeted delivery of carmustine using chitosan coated nanoparticles via nasal route for glioblastoma treatment

S Ahmad, I Khan, J Pandit, NA Emad, S Bano… - International Journal of …, 2022 - Elsevier
This study aims to develop chitosan-coated PLGA nanoparticles intended for nose-to-brain
delivery of carmustine. Formulations were prepared by the double emulsion solvent …

Development of a polysaccharide-based hydrogel drug delivery system (DDS): An update

J Pushpamalar, P Meganathan, HL Tan, NA Dahlan… - Gels, 2021 - mdpi.com
Delivering a drug to the target site with minimal-to-no off-target cytotoxicity is the major
determinant for the success of disease therapy. While the therapeutic efficacy and …

Application of chitosan with different molecular weights in cartilage tissue engineering

R Zhang, SJ Chang, Y Jing, LY Wang, CJ Chen… - Carbohydrate …, 2023 - Elsevier
Cartilage tissue engineering involves the invention of novel implantable cartilage
replacement materials to help heal cartilage injuries that do not heal themselves, aiming to …