Since the accidental discovery of the anticancer properties of cisplatin more than half a
century ago, significant efforts by the broad scientific community have been and are currently …

It is one of the challenging works to deal with second major cause of death due to cancer
and to reduce the mortality rate caused by this. Researchers have been finding various …

In recent years, Ru (II) complexes have gained high importance in medicinal chemistry due
to their significant anti-cancer activities, which are directly related to their DNA binding …

As an important member of reactive oxygen species, hydrogen peroxide (H 2 O 2) plays a
key role in oxidative stress and cell signaling. Abnormal levels of H 2 O 2 in lysosomes can …

A series of 1H-imidazo [4, 5-f][1, 10] phenanthroline derivatives functionalized at 2-position
with chiral, and conformationally flexible polyhydroxy alkyl chains derived from …

A series of Re (I) carbonyl complexes with the 1H-imidazo [4, 5-f][1, 10] phenanthroline
(imphen) ligand functionalized with electron-donating amine groups attached to the …

The extreme toxicity of innocuous organophosphate (OP) nerve agents poses a significant
public health risk. Developing an efficient sensing and detection system is crucial to contain …

Here we present a novel family of carbohydrate conjugates based on the 2-aryl-imidazo [4, 5-
f][1, 10] phenanthroline core modified with carbohydrates (carb-APIPs). The hybrid …

Although there are various treatment options for cancer, this disease still has caused an
increasing number of deaths, demanding more efficient, selective and less harmful drugs …

As one of the most abundant biothiols in cells, glutathione (GSH) usually exists in a dynamic
equilibrium of oxidized glutathione (GSSG) and reduces glutathione redox, and plays an …