Toll-Like Receptor 4 (TLR4) signal pathway plays an important role in initiating the innate
immune response and its activation by bacterial endotoxin is responsible for chronic and …

Excess alcohol exposure leads to alcoholic liver disease (ALD), a predominant cause of
liver-related morbidity and mortality worldwide. In the past decade, increasing attention has …

Alcoholic hepatitis is an acute, inflammatory liver disease associated with high morbidity and
mortality both in the short term and long term. Alcoholic hepatitis often arises in patients with …

Introduction Alcohol-induced intestinal dysbiosis is central to the development of the severe
alcoholic liver disease. We present the first study to compare outcomes in patients of severe …

Background Alcoholic liver disease (ALD) represents a chronic wide-spectrum of liver injury
caused by consistently excessive alcohol intake. Few satisfactory advances have been …

Excessive alcohol consumption leads to damage to the organs of the body. More
importantly, the liver is majorly affected organ upon alcohol consumption for most of the …

Severe alcoholic hepatitis (SAH) is a deadly liver disease without an effective medical
therapy. Although SAH mortality is known to correlate with hepatic accumulation of immature …

Alcohol use accounts for a large variety of diseases, among which alcoholic liver injury (ALI)
poses a serious threat to human health. In order to overcome the limitations of …

Targeted therapy is an emerging treatment strategy for alcoholic liver disease (ALD).
Inflammation plays an important role in the occurrence and development of ALD, and is a …

Alcoholic liver disease (ALD) due to chronic alcohol consumption is a significant global
disease burden and a leading cause of mortality. Alcohol abuse induces a myriad of …