Joint pain is the hallmark symptom of osteoarthritis (OA) and the main reason for patients to
seek medical assistance. OA pain greatly contributes to functional limitations of joints and …

Objective: To collect the available evidence about the effectiveness of pain neuroscience
education (PNE) on pain, disability, and psychosocial factors in patients with chronic …

Background Low back pain is highly prevalent and the main cause of years lived with
disability (YLDs). We present the most up-to-date global, regional, and national data on …

Objective To evaluate the global burden of musculoskeletal (MSK) disorders, as well as the
five common conditions, and their relevant risk factors from 1990 to 2019. Design Data from …

Oxidative stress and inflammation are common pathological mechanisms for the
progression of tissue degeneration. Epigallocatechin-3-gallate (EGCG) features antioxidant …

Background This study describes the global epidemiology and trends associated with neck
pain. Global Burden of Disease data collected between 1990 and 2019 were used to …

Abstract Background/Objective Intervertebral disc (IVD) degeneration (IVDD) that greatly
affected by regional biomechanical environment is a major cause of low back pain …

Background: The global burden of chronic low back pain (CLBP) is a major concern in
public health. Several CLBP epidemiological studies have been conducted in high-income …

The biodegradable hydrogels with a 3D network structure have potential applications in
bone tissue engineering. Here, inspired by natural bone, the novel organic-inorganic …

Background: The role of self-management in health promotion, as well as prevention and
rehabilitation, is increasing through the use of mobile health (mHealth) apps. Such mHealth …