Epidemiology, staging, and management of multiple myeloma

SA Padala, A Barsouk, A Barsouk, P Rawla, A Vakiti… - Medical …, 2021 - mdpi.com
Multiple myeloma (MM) is a plasma cell disorder that is on the rise throughout the world,
especially in the US, Australia, and Western Europe. In the US, MM accounts for almost 2 …

Venous and Arterial Thromboembolism in Patients With Cancer: JACC: CardioOncology State-of-the-Art Review

L Gervaso, H Dave, AA Khorana - Cardio Oncology, 2021 - jacc.org
Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism,
represents a major cause of morbidity and mortality in patients with cancer. Arterial …

NCCN Guidelines® insights: multiple myeloma, version 3.2022: featured updates to the NCCN guidelines

NS Callander, M Baljevic, K Adekola… - Journal of the National …, 2022 - jnccn.org
The NCCN Guidelines for Multiple Myeloma provide recommendations for diagnosis, initial
workup, treatment, follow-up, and supportive care for patients with various plasma cell …

Immunomodulatory drugs in multiple myeloma: mechanisms of action and clinical experience

SA Holstein, PL McCarthy - Drugs, 2017 - Springer
Over the last two decades, the outcomes for patients with multiple myeloma, a plasma cell
malignancy, have dramatically improved. The development of the immunomodulatory drugs …

Smoldering multiple myeloma

SV Rajkumar, O Landgren… - Blood, The Journal of the …, 2015 - ashpublications.org
Smoldering multiple myeloma (SMM) is an asymptomatic clonal plasma cell disorder. SMM
is distinguished from monoclonal gammopathy of undetermined significance by a much …

Predicting venous thromboembolism in multiple myeloma: development and validation of the IMPEDE VTE score

KM Sanfilippo, S Luo, TF Wang, M Fiala… - American journal of …, 2019 - Wiley Online Library
Venous thromboembolism (VTE) is a common cause of morbidity and mortality among
patients with multiple myeloma (MM). The International Myeloma Working Group (IMWG) …

How I manage monoclonal gammopathy of undetermined significance

RS Go, SV Rajkumar - Blood, The Journal of the American …, 2018 - ashpublications.org
Monoclonal gammopathy of undetermined significance (MGUS) is, in many ways, a unique
hematologic entity. Unlike most hematologic conditions in which the diagnosis is intentional …

IgG replacement in multiple myeloma

A Wonnaparhown, T Hilal, J Squire, C Freeman… - Blood cancer …, 2024 - nature.com
T cell engagers (TCE) such as chimeric antigen receptor (CAR) T cell therapy and bispecific
antibodies (BiAbs) for the treatment of multiple myeloma (MM) have significantly improved …

Thrombosis in patients with myeloma treated in the Myeloma IX and Myeloma XI phase 3 randomized controlled trials

CA Bradbury, Z Craig, G Cook, C Pawlyn… - Blood, The Journal …, 2020 - ashpublications.org
Newly diagnosed multiple myeloma (NDMM) patients treated with immunomodulatory drugs
are at high risk of venous thromboembolism (VTE), but data are lacking from large …

Epidemiology, genetics and treatment of multiple myeloma and precursor diseases

K Hemminki, A Försti, R Houlston… - International journal of …, 2021 - Wiley Online Library
Multiple myeloma (MM) is a hematological malignancy caused by the clonal expansion of
plasma cells. The incidence of MM worldwide is increasing with greater than 140 000 …