New biomarkers are being evaluated for their ability to advance the management of patients
with heart failure. Despite a large pool of interesting candidate biomarkers, besides …

Mass spectrometry plays a key role in relative quantitative comparisons of proteins in order
to understand their functional role in biological systems upon perturbation. In this review, we …

Adoption of targeted mass spectrometry (MS) approaches such as multiple reaction
monitoring (MRM) to study biological and biomedical questions is well underway in the …

Targeted mass spectrometry (MS) is becoming widely used in academia and in
pharmaceutical and biotechnology industries for sensitive and quantitative detection of …

Abstract Plasma Proteome Database (PPD; http://www. plasmaproteomedatabase. org/) was
initially described in the year 2005 as a part of Human Proteome Organization's (HUPO's) …

Background Meat quality is a prerequisite to the consumer's acceptability and industrial
profitability. Post-translational modifications, changes in myofibrillar protein degradation and …

An enormous amount of research effort has been devoted to biomarker discovery and
validation. With the completion of the human genome, proteomics is now playing an …

In its early years, mass spectrometry (MS)-based proteomics focused on the cataloging of
proteins found in different species or different tissues. By 2005, proteomics was being used …

Over the past decade, chemical labeling with isobaric tandem mass tags, such as isobaric
tags for relative and absolute quantification reagents (iTRAQ) and tandem mass tag (TMT) …

Biotechnology increasingly delivers highly promising protein-based biopharmaceutical
candidates to the drug development funnel. For successful biopharmaceutical drug …