Methylene blue is used primarily in the treatment of patients with methemoglobinemia. Most
recently, methylene blue has been used as a treatment for refractory distributive shock from …

Objective: This study was conducted to reassess the concepts established over the past 20
years, in particular in the last 5 years, about the use of methylene blue in the treatment of …

Infusion of methylene blue in human septic shock: A pilot, r... : Critical Care Medicine Infusion
of methylene blue in human septic shock: A pilot, randomized, controlled study : Critical Care …

The aim of our study was to assess the effect of methylene blue infusion on plasma levels of
cytokines in severe sepsis. In a prospective, randomized, double-blind, placebo-controlled …

Does methylene blue administration to septic shock patients... : Critical Care Medicine Does
methylene blue administration to septic shock patients affect vascular permeability and blood …

Methylene blue (MB), generic name methylthioninium (C16H18ClN3 S· 3H2O), is a blue dye
synthesized in 1876 by Heinrich Caro for use as a textile dye and used in the laboratory and …

Systemic inflammatory response can be associated with clinically significant and, at times,
refractory hypotension. Despite the lack of uniform definitions, this condition is frequently …

Vasodilatory shock after cardiopulmonary bypass is a common complication requiring
treatment with high doses of inotropes and prolonged stays in the intensive care unit. The …

Current hemodynamic monitoring of critically ill patients is mainly focused on monitoring of
pressure-derived hemodynamic variables related to systemic circulation. Increasingly …

Methods Twenty consecutive patients with refractory septic shock, which was defined as
shock refractory to a dopamine infusion of more than 20 µg/kg/min with the appropriate use …