The chemistry and biological activities of N-acetylcysteine

Y Samuni, S Goldstein, OM Dean, M Berk - Biochimica et Biophysica Acta …, 2013 - Elsevier
BACKGROUND: N-acetylcysteine (NAC) has been in clinical practice for several decades. It
has been used as a mucolytic agent and for the treatment of numerous disorders including …

The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer

E Middleton Jr, C Kandaswami… - Pharmacological reviews, 2000 - Elsevier
Flavonoids are nearly ubiquitous in plants and are recognized as the pigments responsible
for the colors of leaves, especially in autumn. They are rich in seeds, citrus fruits, olive oil …

Drug-induced liver toxicity and prevention by herbal antioxidants: an overview

D Singh, WC Cho, G Upadhyay - Frontiers in physiology, 2016 - frontiersin.org
The liver is the center for drug and xenobiotic metabolism, which is influenced most with
medication/xenobiotic-mediated toxic activity. Drug-induced hepatotoxicity is common and …

Review of toxicological assessment of d-limonene, a food and cosmetics additive

C Ravichandran, PC Badgujar, P Gundev… - Food and Chemical …, 2018 - Elsevier
Abstract R-(+)-limonene (d-limonene) is a commonly used flavor additive in food, beverages
and fragrances for its pleasant lemon-like odor. Considering its increasing applications, it's …

New applications and mechanisms of action of saffron and its important ingredients

SZ Bathaie, SZ Mousavi - Critical reviews in food science and …, 2010 - Taylor & Francis
Saffron (Crocus sativus L.) has been an important subject of interest for research teams in
the past two decades because of its various biological properties. Chemical analysis has …

Mechanisms of N-acetylcysteine in the prevention of DNA damage and cancer, with special reference to smoking-related end-points

S De Flora, A Izzotti, F D'Agostini… - …, 2001 - academic.oup.com
Although smoking cessation is the primary goal for the control of cancer and other smoking-
related diseases, chemoprevention provides a complementary approach applicable to high …

Safety Evaluation And Risk Assessment Of d-Limonene

YW Kim, MJ Kim, BY Chung, DY Bang… - Journal of Toxicology …, 2013 - Taylor & Francis
d-Limonene, a major constituent of citrus oils, is a monoterpene widely used as a
flavor/fragrance additive in cosmetics, foods, and industrial solvents as it possesses a …

Molecular mechanisms for the anti-cancer effects of diallyl disulfide

L Yi, Q Su - Food and chemical toxicology, 2013 - Elsevier
Considerable evidence in recent years suggests that garlic has anti-proliferative effects
against various types of cancer. Garlic contains water-soluble and oil-soluble sulfur …

[PDF][PDF] The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer

JR Elliott Middleton, C Kandaswami… - Pharmacol Rev, 2000 - academia.edu
Flavonoids are nearly ubiquitous in plants and are recognized as the pigments responsible
for the colors of leaves, especially in autumn. They are rich in seeds, citrus fruits, olive oil …

Retinoids in cancer chemoprevention

R Lotan - The FASEB Journal, 1996 - Wiley Online Library
Naturally occurring and synthetic vi‐tamin A metabolites and analogs (retinoids) inhibit
tumor development in a variety of cellular, animal, and patient studies. They suppress …