Globins play a key role in regulating nitric oxide (NO) levels in all forms of life. Five key
reactions of NO with mammalian muscle myoglobin (Mb) and red blood cell hemoglobin …

Although major progress has recently been achieved through ex situ methods, there is still a
lack of understanding of the behavior of the active center in non-precious metal Fe–N/C …

Neuroglobin (Ngb) is a six-coordinate globin that can catalyze the reduction of nitrite to nitric
oxide. Although this reaction is common to heme proteins, the molecular interactions in the …

Abstract Nitrite (NO 2−) interacts with myoglobin (Mb) and hemoglobin (Hb) behaving as a
ligand of both the ferrous (ie, Mb (II) and Hb (II)) and ferric (ie, Mb (III) and Hb (III)) forms …

In human atherosclerosis the development of a cell-poor lipid-rich core is an important
feature of atheromatous plaque formation. The core is characterized by extracellular lipid …

The phenomenon known as renal “ischemic preconditioning,” whereby an initial ischemic
insult induces resistance against subsequent kidney damage, has been well established in …

The autocatalytic reaction between nitrite and the oxy form of globins involves free radicals.
For myoglobin (Mb), an initial binding of nitrite to the iron-coordinated oxygen molecule was …

Nitrite is a common additive used during meat curing to prevent microbial contamination and
retain an attractive red color in the product. However, the effects of nitrite on Fenton …

We investigated in this work the strength of metal–ligand bonding in complexes formed
between Fe (III)-, Mn (III)-and Co (III)-myoglobin and methanol, water, nitrite, and azide …

The globular dioxygen binding heme protein myoglobin (Mb) is present in several species.
Its interactions with the simple nitrogen oxides, namely, nitric oxide (NO) and nitrite, have …