Targeted microglial attenuation through Dendrimer–drug conjugates improves Glaucoma neuroprotection

I Pitha, S Kambhampati, A Sharma, R Sharma… - …, 2023 - ACS Publications
Retinal microglial/macrophage activation and optic nerve (ON) microglial/macrophage
activation are glaucoma biomarkers and potential therapeutic targets for this blinding …

Preferential and increased uptake of hydroxyl-terminated PAMAM dendrimers by activated microglia in rabbit brain mixed glial culture

Y Alnasser, SP Kambhampati, E Nance, L Rajbhandari… - Molecules, 2018 - mdpi.com
Polyamidoamine (PAMAM) dendrimers are multifunctional nanoparticles with tunable
physicochemical features, making them promising candidates for targeted drug delivery in …

Transcriptome profiling of hippocampus after cerebral hypoperfusion in mice

Z Zhang, Z Guo, P Jin, H Yang, M Hu, Y Zhang… - Journal of Molecular …, 2023 - Springer
Chronic cerebral hypoperfusion (CCH) is considered to be one of the major mechanism in
the pathogenesis of vascular cognitive impairment (VCI). Increased inflammatory cells …