The efficacy of Paxlovid against COVID-19 is the result of the tight molecular docking between Mpro and antiviral drugs (nirmatrelvir and ritonavir)

AA Dawood - Advances in Medical Sciences, 2023 - Elsevier
Purpose Currently, a number of medications for coronavirus disease 2019 (COVID-19)
treatment are tested in clinical trials; however, credible clinical studies are becoming …

Increasing the frequency of omicron variant mutations boosts the immune response and may reduce the virus virulence

AA Dawood - Microbial Pathogenesis, 2022 - Elsevier
The coronavirus has posed a serious threat to the world since its discovery in Wuhan in
2019. Beta, gamma, delta, and the final omicron variants have emerged as a result of …

Compatibility of the Ligand Binding Sites in the Spike Glycoprotein of COVID-19 with those in the Aminopeptidase and the Caveolins 1, 2 Proteins

AA Dawood, MA Altobje… - Research Journal of …, 2021 - indianjournals.com
A novel severe viral pneumonia emerged in Wuhan city, China, in December 2019. The
spike glycoprotein of the SARS-CoV-2 plays a crucial role in the viral entry to the host cell …

Influence of SARS-CoV-2 variants' spike glycoprotein and RNA-dependent RNA polymerase (nsp12) mutations on remdesivir docking residues

A Dawood - Med Immuno Rus, 2022 - elibrary.ru
Rapid emergence and evolution of novel SARS-CoV-2 variants has raised concerns about
their potential impact on efficiency of currently available vaccines. Among the most …

Implementation of immuno-chemoinformatics approaches to construct multi-epitope for vaccine development against Omicron and Delta SARS-CoV-2 variants

AA Dawood - Vacunas (English Edition), 2022 - Elsevier
Background The new coronavirus is still a life-threatening menace, because of its changing
nature and capacity to produce many mutations to bypass the immune system. The …

[HTML][HTML] Identification of surface glycoprotein mutations of SARS-CoV-2 in isolated strains from Iraq

BI Jasim - Медицинская иммунология, 2022 - cyberleninka.ru
Background: The global pandemic of coronavirus disease is a societal, economic, and
publichealth crisis that is still underway. The spike glycoprotein of SARS-CoV-2 is one of the …

Determination of binding affinity of tunicamycin with SARS-CoV-2 proteins: Proteinase, protease, nsp2, nsp9, ORF3a, ORF7a, ORF8, ORF9b, envelope and RBD of …

AA Dawood - Vacunas, 2023 - Elsevier
Introduction Despite the availability of several COVID-19 vaccines, the incidence of
infections remains a serious issue. Tunicamycin (TM), an antibiotic, inhibited tumor growth …

Влияние мутационных вариантов спайкового гликопротеина и РНК-зависимой РНКполимеразы (nsp12) SARS-CoV-2 на участки стыковки с ремдесивиром

АА Давуд - Медицинская иммунология, 2022 - mimmun.ru
Аннотация В связи с быстрым развитием и эволюцией новых вариантов SARS-CoV-2
возникли проблемы, касающиеся их потенциального влияния на эффективность …

Идентификация мутаций поверхностного гликопротеина SARS-CoV-2 в штаммах, изолированных в Ираке

АА Давуд, БИ Ясим… - Медицинская …, 2022 - mimmun.ru
Аннотация Глобальная пандемия коронавирусной инфекции стала длительной
кризисной ситуацией для общества, экономики и здравоохранения, которая …

[HTML][HTML] Dampening of proteomics activity associated with the COVID-19 patients afflicted with asthma based on gene expression pattern

AA Dawood - Journal of microbiology, epidemiology and …, 2024 - microbiol.crie.ru
Introduction. It is established that the severity of SARS-CoV-2 infections varies between
individuals without underlying health conditions and those with chronic illnesses like …